2010 Fiscal Year Final Research Report
The role of Filamin A in skeletalgenesis.
| Project/Area Number |
22890216
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
General pharmacology
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| Research Institution | Ritsumeikan University |
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Principal Investigator |
FUJITA Takashi Ritsumeikan University, 薬学部, 准教授 (30319793)
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| Project Period (FY) |
2010
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| Keywords | Filamin A / Runx2 / 骨芽細胞 / 軟骨細胞 / 細胞分化 / 相互作用 / Cbfb |
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| Research Abstract |
The role of Filamin A in skeletalgenesis.
I previously identified Filamin A as a Runx2-binding factor. Current study focused on Filamin A action on skeletalgenesis. Filamin A failed to influence to Runx-dependent transcriptional activity, while inhibited chondrocytes differentiation.
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