2022 Fiscal Year Research-status Report
Interaction of non-Newtonian fluids with deformable structures in microscale biological processes
| Project/Area Number |
22K14184
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| Research Institution | Okinawa Institute of Science and Technology Graduate University |
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Principal Investigator |
VARCHANIS Stylianos 沖縄科学技術大学院大学, マイクロ・バイオ・ナノ流体ユニット, ポストドクトラルスカラー (30913462)
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| Project Period (FY) |
2022-04-01 – 2024-03-31
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| Keywords | Viscoelastic / FSI / Flow instability / Porous media |
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| Outline of Annual Research Achievements |
In FY2022, we developed the tools and laid the foundations for making the key in-silico experiments. Initially, we developed the algorithm and implemented it in the in-house parallel FE code. We performed strict mesh and time-step refinement convergence tests for VFSI past a single deformable cylinder. We found that the method exhibits second-order accuracy in space and time. We also validated the numerical results with microfluidic experiments of viscoelastic flow past two cantilevered cylinders; semi-quantitative agreement was achieved. All the results are summarized in a manuscript that will be submitted in the journal "Computer Methods in Applied Mechanics and Engineering".
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| Current Status of Research Progress |
Current Status of Research Progress
1: Research has progressed more than it was originally planned.
Reason
The project has progressed very well through FY2022. As initially expected, the numerical algorithm has been developed and validated. There is sufficient time in
FY2023 to carry out the bulk of the detailed simulations and elucidate the underlying physics of the process. The rather quick progress was mainly due to the large amount of preliminary research conducted prior to the beginning of the project. Additionally, the Scientific Computing and Data Analysis section of Research Support Division at OIST provided valuable help regarding coding and implementation of the algorithm.
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| Strategy for Future Research Activity |
We accomplished the planned objectives for FY2022. In FY2023, we will carry out the bulk of the detailed simulations. We will start with simulation of the base (reference) case for increasing flow rates. Then we will proceed to a wide parametric analysis the rheological properties of the viscoelastic fluid and the solid, followed by a parametric analysis regarding the geometrical properties of the physical domain. Finally, we will carry out a detailed data analysis and derive scaling relationships to relate the properties of the fluid, the solid, and the geometry with the macroscopically observed quantities (e.g., apparent permeability, slip length, frequency of oscillations). The results will be summarized in two papers. One for flow past a single deformable cylinder in a straight channel and a second one for flow past a periodic array of deformable cylinders.
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