Effect of stannous fluoride containing toothpaste on root caries prevention using nondestructive testing and solid-state NMR

2023 Fiscal Year Final Research Report

• Project/Area Number: 22K17047
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 57030:Conservative dentistry-related
• Research Institution: Nihon University
• Principal Investigator: SHIBASAKI Sho 日本大学, 歯学部, 助教 (70822633)
• Project Period (FY): 2022-04-01 – 2024-03-31
• Keywords: フッ化スズ / 根面齲蝕 / 齲蝕予防 / 超音波透過法 / 固体核磁気共鳴法

Outline of Final Research Achievements

The used toothpastes were the stannous fluoride containing tooth paste (ST) and the sodium fluoride containing tooth paste (SO). Distilled water was used instead of toothpastes as the control group. In the results of ultrasonic measurements, all the brushing groups showed no significant differences in V among the brushing period. In the results of KHN, although all the groups showed decreased KHN with increased brushing periods, the KHN of ST were significantly higher than those of the other groups. From the results of this study, the ability of prevention root caries in stannous fluoride containing toothpaste might be equal or greater when compared to that of sodium fluoride containing toothpaste.

Free Research Field

保存治療系歯学

Academic Significance and Societal Importance of the Research Achievements

超高齢社会の進行に伴った高齢者の残存歯数の増加によって，根面齲蝕が増加傾向にある。根面齲蝕はその性質上，修復操作が困難となる症例も多い。また根面齲蝕を有する高齢者は通院を伴う歯科医院での治療が困難となる場合も多く，セルフケアを主体とした根面齲蝕予防が重要と考えられる。特に，フッ化スズが有する抗齲蝕性，抗炎症作用，象牙質知覚過敏抑制，抗菌性，口臭および酸蝕抑制効果は特筆すべきものであり，フッ化スズ含有歯磨剤を根面齲蝕予防に応用できれば歯科領域への貢献は大であると考えられる。