2023 Fiscal Year Research-status Report
Nutritional approach for the cognitive frailty prevention: a 22-years cohort study of older Japanese community-dwellers.
| Project/Area Number |
22K17847
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| Research Institution | National Center for Geriatrics and Gerontology |
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Principal Investigator |
張 シュ 国立研究開発法人国立長寿医療研究センター, 研究所 老年学・社会科学研究センター, 研究員 (00874471)
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| Project Period (FY) |
2022-04-01 – 2026-03-31
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| Keywords | risk factors / cognitive frailty / cohort |
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| Outline of Annual Research Achievements |
This study aims to elucidate: 1) dietary factors that play important roles in preventing cognitive frailty (CF) (through different pathways); 2) possible mechanisms of any associations identified; and 3) risk factors modifying nutrition approaches for preventing and improving CF.
My main task this year was to collect data on subjective cognitive decline using the Memory Complaint Questionnaire in Japanese (MAC-Q-J) in the NILS-LSA 10th wave survey. In addition, I examined the effects of various risk factors on the transition from robustness to CF using 14 years of cognitive function and frailty data. I found differences in the effects of different risk factors on the transition pathways in a multi-state model. This result suggests the need for targeted interventions for CF prevention.
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| Current Status of Research Progress |
Current Status of Research Progress
2: Research has progressed on the whole more than it was originally planned.
Reason
The 10th survey is well underway and gathering useful information for further analysis. It provides useful data for defining CF in the future.
Based on the existing risk factor assessment data and 14 years of cognitive function and frailty data, I was able to secure a certain number of subjects and examine association between risk factors and CF development. The findings obtained will be submitted to international academic journals.
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| Strategy for Future Research Activity |
I will utilize the data collected using the MAC-Q in the new round of the NILS-LSA survey (10th) to more accurately determine the CF status of the participants. These data will be further analyzed.
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| Causes of Carryover |
Due to the analysis taking longer than initially planned, we have postponed the submission of documents to the next fiscal year. Additionally, because the preparation of the 10th survey has taken longer than anticipated, we have carried over funds from this year's 10th survey to the next fiscal year. The amount incurred in the next fiscal year will be used primarily for the 10th NILS-LSA survey, as well as costs associated with conference presentations and paper publication.
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