2022 Fiscal Year Annual Research Report
| Project/Area Number |
22J11615
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| Allocation Type | Single-year Grants |
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| Research Institution | Hokkaido University |
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Principal Investigator |
WANG YUBO 北海道大学, 大学院総合化学院, 特別研究員(DC2)
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| Project Period (FY) |
2022-04-22 – 2024-03-31
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| Keywords | cyclic PEG / silver nanoparticles / polymer topology / poly(ethylene glycol) |
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| Outline of Annual Research Achievements |
The present research result shows that cyclic poly(ethylene glycol)(c-PEG) tends to yield smaller and narrowly dispersed AgNPs when employed during the Tollens synthesis in comparison with linear PEG, where smaller and narrowly dispersed metal nanoparticles are desired in various applications. Furthermore, the AgNPs with c-PEG exhibited superior stabilizing properties against NaCl despite the smaller size. These results clearly indicate the cyclized polymers endow AgNPs with the superior stability compared with the linear counterparts. The enhanced colloidal stability through the use of c-PEG would enable applications in biological systems where its high salt resistance can be exploited. It is proved that c-PEG exhibits superior dispersion stabilization to metal nanoparticles.
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| Current Status of Research Progress |
Current Status of Research Progress
2: Research has progressed on the whole more than it was originally planned.
Reason
The purpose of my research is to disperse nanoparticles by the polymer topology effect. Until now, I have applied cyclic poly(ethylene glocol)(c-PEG) to disperse gold or silver nanoparticles or some proteins in aqueous solutions. However, the dispersed nanoparticles are belonging metal nanoparticles. In the future, some nonmetal nanoparticles such as fullerene C60 or C70 will be also dispersed by the same c-PEG based on the polymer topology effect. It is expected that the present formulation can be widely applied due to the chemical homogeneity of c-PEG with physisorption. Furthermore, cyclization and physisorption require no chemical modification on the repeating units of the polymer chain, which is excellent match for the biocompatibility of PEG.
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| Strategy for Future Research Activity |
In the future, this formulation of cyclic polymer will also be applied on other metal nanoparticles due to the physisorption. The utilization of polymer topology effect towards the stability of nanoparticles will open a new vision based on this result. Not only the metal nanoparticles, other nanoparticles such as fullerene (C60, or C70) have also been proved the dispersity in water by using cyclic polymers. Based on this point, the adsorption capacity between non-metal nanoparticles and cyclic polymers will also be simulated by MD method, which is expected that c-PEG can be absorbed on the surface of nanoparticles. Moreover, the thickness or morphology of c-PEG surrounding silver nanoparticles will be performed by using small-angle X-ray scattering or wide-angle X-ray. scattering.
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