Preparation of unique organic phases for high molecular recognitive HPLC

2014 Fiscal Year Final Research Report

• Project/Area Number: 23245018
• Research Category: Grant-in-Aid for Scientific Research (A)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Analytical chemistry
• Research Institution: Kumamoto University
• Principal Investigator: IHARA Hirotaka 熊本大学, 自然科学研究科, 教授 (10151648)
• Co-Investigator(Kenkyū-buntansha): TAKAFUJI Makoto 熊本大学, 大学院自然科学研究科, 准教授 (50332086) ; NAGAOKA Shoji 熊本県産業技術センター, 研究主幹 (10227994) ; GANAPATHY Hullathy 熊本大学, 大学院先導機構, 助教 (90551276) ; SAWADA Tsuyoshi 熊本大学, 大学院自然科学研究科, 准教授 (90240902) ; TOMINAGA Masoto 熊本大学, 大学院自然科学研究科, 准教授 (70264207)
• Project Period (FY): 2011-04-01 – 2015-03-31
• Keywords: 液体クロマドクラフィ / 分子形状識別 / 自己組織化 / 界面・界面物性 / ポリイオン液体

Outline of Final Research Achievements

In this research project, we have targeted to create a new class of molecular recognitive materials for high performance liquid chromatography. For this purpose, we did not use any biomaterial and supramolecular cyclic compound as a molecular recognitive moiety, but rather selected a linear polymer because we considered for controlling the selectivity through molecular design. In concrete terms, we have designed unique organic phases based on integration of weak interaction groups such as a carbonyl group and a pi-electron-rich moiety on a polymer chain. As a result, we have developed various organic phases indicating high selectivities for isomers having chemically similar properties, and then these main results have been published as 28 international journal papers.

Free Research Field

高分子機能材料