2013 Fiscal Year Final Research Report
Formation process of self-organized nano-pore arrays on metal substrates and their applications to metallic biomaterials
| Project/Area Number |
23246128
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Material processing/treatments
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| Research Institution | Osaka University |
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Principal Investigator |
FUJIMOTO SHINJI 大阪大学, 工学(系)研究科(研究院), 教授 (70199371)
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| Co-Investigator(Kenkyū-buntansha) |
TSUCHIYA Hiroaki 大阪大学, 大学院工学研究科, 准教授 (50432513)
MIYABE Sayaka 大阪大学, 大学院工学研究科, 助教 (50584132)
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| Co-Investigator(Renkei-kenkyūsha) |
HIROMOTO Sachiko 独立行政法人物質・材料研究機構 (00343880)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Keywords | ナノホールアレイ / 自己組織化 / 生体材料 / 生体適合性 / 腐食防食 / 電気化学 |
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| Research Abstract |
The present work examined the electrochemical formation of self-organized nano-porous structures on metallic biomaterials and evaluates their biocompatibility. Self-organized nano-porous structures were formed on stainless steels, titanium and cobalt-chromium alloy although optimized condition for the pore formation was different depending on the substrates. Cell proliferation was enhanced on porous Type316L stainless steel surfaces compared to a flat stainless steel surface. Repassivation that is one of the most essential factors to suppress metal dissolution induced by deformation was facilitated by the presence of nano-porous structures on stainless steel surface. These findings demonstrated that the formation of self-organized nano-porous structure on stainless steel surface can improve the biocompatibility as well as corrosion resistance during the deformation of stainless steel.
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