Realization of High Performance Real Time Arteriosclerosis Diagnosis System by Soft Computing

2013 Fiscal Year Final Research Report

• Project/Area Number: 23300086
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Sensitivity informatics/Soft computing
• Research Institution: Yamaguchi University
• Principal Investigator: UCHINO Eiji 山口大学, 理工学研究科, 教授 (30168710)
• Co-Investigator(Kenkyū-buntansha): SUETAKE Noriaki 山口大学, 大学院・理工学研究科, 准教授 (80334051) ; HIRO Takafumi 日本大学, 医学部, 准教授 (10294638)
• Project Period (FY): 2011-04-01 – 2014-03-31
• Keywords: 血管内超音波法 / 動脈硬化 / 心筋梗塞 / プラーク / 組織性状判別 / ソフトコンピューティング / 実用化

Research Abstract

Rupture of plaque piled up in the coronary artery causes acute coronary syndromes (ACS) including arteriosclerosis which results in myocardial infarction leading to death in the worst case. Plaque is classified into stable plaque (easy to rupture) and unstable plaque according to the structure of plaque. Therefore for the early detection and diagnosis of ACS, tissue characterization of coronary plaque with high accuracy is essential. In this research, soft computing based signal analysis imitating the information processing scheme in the human brain is applied for the tissue characterization of coronary plaque. It enabled the high performance diagnosis system giving 2D and/or 3D imaging of characterized plaque on the bed side.

Research Products

• [Journal Article] Hybrid Boundary Detection Method for Image with Application to Coronary Plaque (2014)
  • Author(s): S. Anam, E. Uchino, and N. Suetake
  • Journal Title: Int. J. Digital Information and Wireless Communications Volume: Vol.4,No.4
  • Peer Reviewed
• [Journal Article] Combining PSO and Fuzzy Inference for the Calculation of Coronary Plaque Boundary in IVUS Image (2014)
  • Author(s): S. Anam, E. Uchino, Misawa and N. Suetake
  • Journal Title: Int. J. of Biomedical Soft Computing and Human Sciences Volume: Vol.19,No.1
  • Peer Reviewed
• [Journal Article] Characterization of Coronary Plaque by Using 2D Frequency Histogram of RF Signal (2014)
  • Author(s): S. Nakao, K. Tokunaga, N. Suetakea n d E. Uchino
  • Journal Title: Soft Computing in Industrial Applications,Advances in Intelligent Systems and Computing Volume: Vol.223 Pages: 187-196
  • Peer Reviewed
• [Journal Article] Tissue Characterization of Coronary Plaque by kNN Classifier with Fractal-based Features of IVUS RF-signal (2013)
  • Author(s): E. Uchino, T. Koga, H. Misawa and N. Suetake
  • Journal Title: J. of Intelligent Manufacturing Volume: (published online)
  • DOI: 10.1007/s10845-013-0793-3
  • Peer Reviewed
• [Journal Article] Plaque Stabilization by Intensive LDL-Cholesterol Lowering Therapy with Atorvastatin is Delayed in Type 2 Diabetic Patients with Coronary Artery Disease-Serial Angioscopic and Intravascular Ultrasound Analysis (2013)
  • Author(s): T. Takayama, T. Hiro, Y. Ueda, J. Honye, S. Komatsu, O. Yamaguchi, Y. Li, J. Yajima, K. Takazawa, S. Nanto, S. Saito, A. Hirayama and K. Kodama
  • Journal Title: J. Cardiol Volume: Vol.61,No.6 Pages: 381-386
  • Peer Reviewed
• [Journal Article] Three Stars of the Constellation of Color Intravascular Ultrasound in the Space of Tissue Characterization of Coronary Plaque (2013)
  • Author(s): T. Hiro
  • Journal Title: J. Cardiol Volume: Vol.61,No.2 Pages: 186-187
  • Peer Reviewed
• [Journal Article] IVUS-Based Coronary Plaque Tissue Characterization Using Weighted Multiple k-Nearest Neighbor (2012)
  • Author(s): E. Uchino, K. Tokunaga, H. Tanaka and N. Suetake
  • Journal Title: Engineering Letters Volume: Vol.20,No.3 Pages: 211-216
  • Peer Reviewed
• [Journal Article] High-Speed Calculation for Tissue Characterization of Coronary Plaque by Employing Parallel Computing Techniques (2011)
  • Author(s): T. Koga, S. Furukawa, E. Uchinoand N. Suetake
  • Journal Title: Int. J. of Circuits, Systems and Signal Processing Volume: Vol.5,No.4 Pages: 435-442
  • Peer Reviewed
• [Presentation] Tissue Characterization of Coronary Plaque by Subspace Method with Consideration to Neighborhood Information of Target Tissue (2014)
  • Author(s): S. Furukawa, E. Uchino, S. Miwa, and N. Suetake
  • Organizer: Proc. of the 2014 Int. Conf. on Artificial Intelligence and Applications (ICAIA 2014)
  • Place of Presentation: The Royal Garden Hotel, Kowloon, Hong Kong, China
  • Year and Date: 2014-03-14
• [Presentation] Application of Bag-of- Keypoints to Tissue Characterization of Coronary Plaque for the Diagnosis of Arteriosclerosis (2014)
  • Author(s): S. Nakao, E. Uchino, S. Furukawa and N. Suetake
  • Organizer: Proc. of 2014 RISP Int. Workshop on Nonlinear Circuits, Communications and Signal Processing (NCSP 2014)
  • Place of Presentation: Waikiki Beach Marriott Resort & Spa, Honolulu, Hawaii, USA
  • Year and Date: 2014-03-03
• [Presentation] Sparse Feature Based Analysis of RF Signal for Coronary Plaque Tissue Classification with Reference to the Neighboring Information of the Target Tissue (2014)
  • Author(s): S. Furukawa, E. Uchino, T. Azetsu, and N. Suetake
  • Organizer: Proc. of the 2014 Int. Conf. on Communications, Signal Processing and Computers (CSCP 2014)
  • Place of Presentation: Lindner Grand Hotel Beau Rivage, Interlaken, Switzerland
  • Year and Date: 2014-02-23
• [Presentation] Classification of Intravascular Ultrasound Signal by Kernel Density Estimation and Bayes Theorem for Identification of Coronary Plaque Tissue (2014)
  • Author(s): H. Tanaka, K. Tokunaga, E. Uchino, and N. Suetake
  • Organizer: Proc. Of the 2014 Int. Conf. on Communications, Signal Processing and Computers (CSCP 2014)
  • Place of Presentation: Lindner Grand Hotel Beau Rivage, Interlaken, Switzerland
  • Year and Date: 2014-02-22
• [Presentation] Coronary Plaque Boundary Detection in Intravascular Ultrasound Image by Using Hybrid Modified Level Set Method and Fuzzy Inference (2013)
  • Author(s): S. Anam, E. Uchinoand N. Suetake
  • Organizer: Proc. of the Second Int. Conf. on Informatics Engineering & Information Science (ICIEIS 2013)
  • Place of Presentation: Advanced Informatics School, University Technology Malaysia (UTM), Kuala Lumpur, Malaysia
  • Year and Date: 2013-11-12
• [Presentation] Coronary Plaque Boundary Calculation in IVUS Image by Modified PMD Filter and Fuzzy Inference (2013)
  • Author(s): S. Anam, E. Uchinoand N. Suetake
  • Organizer: Proc. of the 20th Int. Conf. on Neural Information Processing (ICONIP 2013)
  • Place of Presentation: EXCO, Daegu, Korea
  • Year and Date: 2013-11-05
• [Presentation] Characterization of Coronary Plaque by Using 2D Frequency Histogram of RF Signal (2012)
  • Author(s): S. Nakao, K. Tokunaga, N. Suetake and E. Uchino
  • Organizer: Proc. of the 17th Online World Conf. on Soft Computing in Industrial Applications (WSC17)
  • Year and Date: 20121210-21
• [Presentation] Parameter Tuning by PSO for Fuzzy Inference-Based Coronary Plaque Extraction in IVUS Image (2012)
  • Author(s): S. Anam, H. Misawa, E. Uchinoand N. Suetake
  • Organizer: Proc. of the Joint 6th Int. Conf. on Soft Computing and Intelligent Systems and 13th Int. Symposium on Advanced Intelligent Systems (SCIS & ISIS 2012)
  • Place of Presentation: Kobe Convention Center, Kobe Portopia Hotel, Kobe, Japan
  • Year and Date: 2012-12-23
• [Presentation] Moving Window-Based Similarity Analysis and Its Application to Tissue Characterization of Coronary Arteries (2012)
  • Author(s): G. Vachkov, E. Uchino, and S. Nakao
  • Organizer: Proc. Of the 2012 Int. Conf. on Bioinformatics (ICB 2012), Best Student Paper Award
  • Place of Presentation: The Royal Garden Hotel, Kowloon, Hong Kong, China
  • Year and Date: 2012-03-16
• [Presentation] Tissue Classification of Coronary Plaque Using Intravascular Ultrasound Method by Extended Multiple k-Nearest Neighbor (2012)
  • Author(s): K. Tokunaga, E. Uchino, H. Tanaka and N. Suetake
  • Organizer: Proc. of the 2012 Int. Conf. on Artificial Intelligence and Applications (ICAIA 2012), Merit for the Conference (Conference Award)
  • Place of Presentation: The Royal Garden Hotel, Kowloon, Hong Kong, China
  • Year and Date: 2012-03-16
• [Presentation] Tissue Characterization of Coronary Plaque by Soft Computing for the Diagnosis of Arteriosclerosis (2012)
  • Author(s): E. Uchino, N. Suetake R. Kubota, T. Koga, T. Hiro, and M. Matsuzaki
  • Organizer: Proc. of the 2012 Int. Symposium on Semiconductor Manufacturing Intelligence (ISMI 2012) & Decision Analysis Symposium 2012 (DAS 2012)
  • Place of Presentation: National Tsing Hua University, Hsinchu, Taiwan
  • Year and Date: 2012-01-06
• [Presentation] Automated Boundary Extraction and Visualization System for Coronary Plaque in IVUS Image by Using Fuzzy Inference-based Method (2011)
  • Author(s): T. Koga, E. Uchinoand N. Suetake
  • Organizer: Proc. of 2011 IEEE Int. Conf. on Fuzzy Systems (FUZZ-IEEE 2011)
  • Place of Presentation: Grand Hyatt Taipei, Taipei, Taiwan
  • Year and Date: 2011-06-29
• [Presentation] Similarity Analysis Based on the Weighted Moving Window for Tissue Characterization of Plaque in Coronary Arteries
  • Author(s): G. Vachkov and E. Uchino
  • Organizer: Proc. Of the 4th Int. Conf. on Intelligent Decision Technologies (IDT 2012)
  • Place of Presentation: Nagaragawa Convention Center, Gifu, Japan
• [Remarks]
  • URL: http://www.ic.sci.yamaguchi-u.ac.jp/
• [Patent(Industrial Property Rights)] スパースコーディングを用いた組織性状判別 (2013)
  • Inventor(s): 内野英治, 末竹規哲, 畔津忠博, 松崎益徳, 廣 高史
  • Industrial Property Rights Holder: 国立大学法人山口大学, 公立大学法人山口県立大学
  • Industrial Property Rights Type: 特許権
  • Industrial Property Number: 第5213173号
  • Filing Date: 2013-03-08
• [Patent(Industrial Property Rights)] 分離測度を用いた重み付け最小二乗法による境界抽出 (2012)
  • Inventor(s): 内野英治, 末竹規哲, 久保田良輔, 松崎益徳, 廣 高史
  • Industrial Property Rights Holder: 国立大学法人山口大学
  • Industrial Property Rights Type: 特許権
  • Industrial Property Number: 第4963278号
  • Filing Date: 2012-04-06
• [Patent(Industrial Property Rights)] 超音波診断装置及び組織性状判別のプログラム (2011)
  • Inventor(s): 内野英治, 末竹規哲, 久保田良輔, 松崎益徳, 廣 高史
  • Industrial Property Rights Holder: 国立大学法人山口大学
  • Industrial Property Rights Type: 特許権
  • Industrial Property Number: 第4839446号
  • Filing Date: 2011-10-14