2013 Fiscal Year Final Research Report
Neural mechanism of flexible cognition and use of symbols: a comparative macaque ECoG and human fMRI study
| Project/Area Number |
23300150
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Fusional brain recording science
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| Research Institution | Niigata University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
NAKAHARA Kiyoshi 高知工科大学, 総合研究所, 教授 (50372363)
KITAGAWA Junichi 新潟大学, 医歯学系, 准教授 (50373006)
KAWASAKI Keisuke 新潟大学, 医歯学系, 助教 (60511178)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Keywords | マカクザル |
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| Research Abstract |
We developed a visual sign system where object categories were symbolically represented by distinct combinations of visual elements. Macaque monkeys (Macaca fuscata) learned to use these composite symbols by combining and decomposing elements. We conducted multichannel electrtocorticographic (ECoG) recording from the prefrontal cortex and inferior temporal cortex of the monkeys. Analyses of event-related spectral perturbation of the prefrontal ECoG signals revealed areal segregation for combination and decomposition of symbol elements in specific frequency band powers. Functional magnetic resonance imaging in healthy human subjects revealed insular activation during reading particularly when segmentation of letterstrings was required compared to segmentation was not required. Furthermore, we tested symmetry of symbolic use in three macaque monkeys. Symbolic association was symmetrically learned in two macaques but not in one animal, indicating the need for further testing.
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[Journal Article] Intrasulcal electrocorticography in macaque monkeys with minimally invasive neurosurgical protocols2011
Author(s)
Matsuo T, Kawasaki K, Osada T, Sawahata H, Suzuki T, Shibata M, Miyakawa N, Nakahara K, Iijima A, Sato N, Kawai K, Saito N, Hasegawa I
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Journal Title
Front Syst Neurosci
Volume: 5
Pages: 34
Peer Reviewed
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[Journal Article] Alternating zones selective to faces and written words in the human ventral occipitotemporal cortex
Author(s)
Matsuo T, Kawasaki K, Kawai K, Majima K, Masuda H, Murakami H, Kunii N, Kamitani Y, Kameyama S, Saito N, Hasegawa I
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Journal Title
Cereb Cortex
Volume: (in press)
DOI
Peer Reviewed
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