2013 Fiscal Year Final Research Report
Neural control and its impairment of flexible stability during human bipedal standing and walking
| Project/Area Number |
23300166
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | Osaka University |
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Principal Investigator |
NOMURA Taishin 大阪大学, 基礎工学研究科, 教授 (50283734)
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| Co-Investigator(Kenkyū-buntansha) |
SAKODA Saburo 国立病院機構刀根山病院, 院長 (00178625)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Keywords | 立位姿勢 / 二足歩行 / 静止立位 / 運動制御 / 非線形力学系 / 間欠制御 / 安定性 / パーキンソン病 |
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| Research Abstract |
We have proposed recently that human upright standing is stabilized in a flexible and robust manner by an intermittent control. In this study, we provided several evidences that support our hypothesis based on mathematical models of postural control and psychophysical experiments. We discussed possibility that a loss of intermittency in the neural control can be a cause of postural instability in patients with Parkinson's disease (PD). Moreover, we investigated a gait symptom called freezing of gait in PD patients, and suggested that a forceful but noisy neural control of interlimb coordination can be a main cause of the freezing of gait.
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