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2013 Fiscal Year Final Research Report

A study of hybrid navigation system for seamless MR image guided surgery

Research Project

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Project/Area Number 23300188
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Medical systems
Research InstitutionShiga University of Medical Science

Principal Investigator

MORIKAWA SHIGEHIRO  滋賀医科大学, 医学部, 教授 (60220042)

Co-Investigator(Kenkyū-buntansha) NAKA Shigeyuki  滋賀医科大学, 医学部, 准教授 (10359771)
KURUMI Yoshimasa  滋賀医科大学, 医学部, 教授 (70205219)
Project Period (FY) 2011-04-01 – 2014-03-31
Keywords低侵襲治療システム / MR画像誘導システム / 手術ロボット
Research Abstract

A novel image navigation system has been successfully developed using a standard high-field MR system and an MR-compatible surgical robot to assist image-guided puncture. With this system, the robot automatically chased the preset target point immediately after the image acquisition without registration process. The safe and optimal puncture route could be selected while monitoring reconstructed images along the needle path. After the puncture of the target, the position and direction of the needle were recorded. MR images for the evaluation of the puncture could be immediately acquired without scout images. Thus, seamless MR image-guided surgical procedures were realized inside and outside the magnet.

  • Research Products

    (59 results)

All 2014 2013 2012 2011

All Journal Article (16 results) (of which Peer Reviewed: 14 results) Presentation (40 results) (of which Invited: 3 results) Book (2 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] Preferred features of a fluorine-19 MRI probe for amyloid detection in the brain2014

    • Author(s)
      Yanagisawa D, Taguchi H, Ibraham NF, Morikawa S, Shiino A, Inubushi T, Hirao K, Shirai N, Sogabe T, Tooyama I
    • Journal Title

      Journal of Alzheimer's Disease

      Volume: 39(3) Pages: 617-31

    • Peer Reviewed
  • [Journal Article] Design, synthesis, and preliminary ex vivo and in vivo evaluation of cationic magnetic resonance contrast agent for rabbit articular cartilage imaging2013

    • Author(s)
      Irie T, Oda K, Shiino A, Kubo M, Morikawa S, Urushiyama N, Aonuma S, Kimura T, Inubushi T, Oohashi T, Komatsu N
    • Journal Title

      Med Chem Commun

      Volume: 4 Pages: 1508-1512

    • Peer Reviewed
  • [Journal Article] Laparoscopic surgery simulator using first person view and guidance force2013

    • Author(s)
      Tagawa K, Tanaka HT, Kurumi Y, Komori M, Morikawa S
    • Journal Title

      Stud Health Technol Inform

      Volume: 184 Pages: 431-5

    • Peer Reviewed
  • [Journal Article] 臓器異型バリエーションの構成的多重解像度モデリング2013

    • Author(s)
      田川和義, 来見良誠, 小森優, 森川茂廣, 田中弘美
    • Journal Title

      電気情報通信学会論文誌

      Volume: D J96-D Pages: 1365-1373

    • Peer Reviewed
  • [Journal Article] A simple way to acquire T_1-weighted MR images of rat liver with respiratory triggering2012

    • Author(s)
      Morikawa S, Murayama H, Fujimoto S, Shiino A, Inubushi T
    • Journal Title

      Magn Reson Imaging

      Volume: 30 Pages: 453-458

    • Peer Reviewed
  • [Journal Article] The profile of hippocampal metabolites differs between Alzheimer`s disease and subcortical ischaemic vascular dementia, as measured by proton magnetic resonance spectroscopy2012

    • Author(s)
      Shiino A, Watanabe T, Shirakashi Y, Kotani E, Yoshimura M, Morikawa S, Inubushi T, Akiguchi I
    • Journal Title

      J Cereb Blood Flow Metab

      Volume: 32 Pages: 805-815

    • Peer Reviewed
  • [Journal Article] Mapping of cerebral metabolic rate using DSC and BOLD MR imaging : a preliminary study2012

    • Author(s)
      Shiino A, Yamauchi H, Morikawa S, Inubushi T
    • Journal Title

      Magn Reson Med Sci

      Volume: 11 Pages: 109-115

    • Peer Reviewed
  • [Journal Article] A 3D Non-Homogeneous FE Model of Human Fingertip Based on MRI Measurements2012

    • Author(s)
      Wang Z, Wang L, Ho VA, Morikawa S, Hirai S
    • Journal Title

      IEEE Transactions on Instrumentation and Measurement (TIM)

      Volume: 61 Pages: 3147-3157

    • Peer Reviewed
  • [Journal Article] Development of instruments to assist accurate puncture of liver tumors for MRI-guided microwave ablation -From a simple spacer to a motorized robot2012

    • Author(s)
      Morikawa S, Naka S, Shiomi H, Murayama H, Murakami K, Tani T, Kurumi Y, Haque A H, Inubushi T
    • Journal Title

      J Microwave Surg

      Volume: 30 Pages: 183-190

  • [Journal Article] Hyperbranched polyglycerol-grafted superparamagnetic iron oxide nanoparticles : synthesis, characterization, functionalization, size separation, magnetic properties, and biological applications2012

    • Author(s)
      Zhao L, Chano T, Morikawa S, Saito Y, Shiino A, Shimizu S, Maeda T, Irie T, Aonuma S, Okabe H, Kimura T, Inubushi T, Komatsu N
    • Journal Title

      Adv Funct Mater

      Volume: 22 Pages: 5107- 5117

    • Peer Reviewed
  • [Journal Article] 一人称視点映像と誘導力提示による腹腔鏡下手術手技のVR 訓練システム2012

    • Author(s)
      田川和義, 田中弘美, 小森優, 来見良誠, 森川茂廣
    • Journal Title

      日本VR 医学会論文誌

      Volume: 10 Pages: 11-18

    • Peer Reviewed
  • [Journal Article] A 3D FE Dynamic Model of Human Fingertip Based on MRI Data2011

    • Author(s)
      Wang Z, Abe Y, Hirai S, Morikawa S
    • Journal Title

      Proc. 2011 IEEE Int. Symp. on Haptic Audio- Visual Environments and Games

      Pages: 8-12

    • Peer Reviewed
  • [Journal Article] An MR Comparison Study of Cardiogenic and Noncardiogenic Pulmonary Edema in Animal Models2011

    • Author(s)
      Fujimoto S, Morikawa S, Inubushi T
    • Journal Title

      J Magn Reson Imaging

      Volume: 34 Pages: 1092-1098

    • Peer Reviewed
  • [Journal Article] Needle insertion simulation by arbitrary Lagrangian- Eulerian method2011

    • Author(s)
      Yamaguchi S, Satake K, Morikawa S, Shirai Y, Tanaka HT
    • Journal Title

      Studies in Health Technology & Informatics

      Volume: 163 Pages: 710-2

    • Peer Reviewed
  • [Journal Article] In vivo detection of amyloid β deposition using ^<19>F magnetic resonance imaging with a ^<19>F containing curcumin derivative in a mouse model of Alzheimer's disease2011

    • Author(s)
      Yanagisawa D, Amatsubo T, Morikawa S, Taguchi H, Urushitani M, Shirai N, Hirao K, Shiino A, Inubushi T, Tooyama I
    • Journal Title

      Neuroscience

      Volume: 184 Pages: 120-127

    • Peer Reviewed
  • [Journal Article] マイクロ波と磁気共鳴画像のめぐり会い2011

    • Author(s)
      森川茂廣, 来見良誠, 仲成幸, 塩見尚礼, 村山浩之, 村上耕一郎, Hasnine A Haque, 犬伏俊郎, 谷徹
    • Journal Title

      J Microwave Surg

      Volume: 29 Pages: 33-38

  • [Presentation] An Analysis of Expert's Hand Movements based on Surgical Process model in Laparoscopic Surgery Training2014

    • Author(s)
      Marutani T
    • Organizer
      20th Korea-Japan Joint Workshop on Frontiers of Computer Vision
    • Place of Presentation
      Okinawa.
    • Year and Date
      20140204-06
  • [Presentation] MR image guided microwave ablation of liver tumors. -From a low field open-configuration system to a high field closed-bore system2013

    • Author(s)
      Morikawa S
    • Organizer
      9th Joint Workshop on Machine Perception and Robotics
    • Place of Presentation
      Kyoto
    • Year and Date
      20131031-1101
    • Invited
  • [Presentation] Evaluation of Haptic Training Methods for Laparoscopic Surgery Skill Transfer2013

    • Author(s)
      Kato T
    • Organizer
      9th Joint Workshop on Machine Perception and Robotics. (MPR2013)
    • Place of Presentation
      Kyoto
    • Year and Date
      20131031-1101
  • [Presentation] A Study on Transferring Veteran's Laparoscopic Surgical Techniques based on Surgical Process Model by Using Trainee's Action Archiving System2013

    • Author(s)
      Marutani Y
    • Organizer
      9th Joint Workshop on Machine Perception and Robotics. (MPR2013)
    • Place of Presentation
      Kyoto
    • Year and Date
      20131031-1101
  • [Presentation] 通常MR 装置と穿刺支援ロボットを組み合わせたシームレス画像ナビゲーション2013

    • Author(s)
      森川茂廣
    • Organizer
      第41回日本磁気共鳴医学会大会
    • Place of Presentation
      徳島市
    • Year and Date
      20130919-21
  • [Presentation] MR 画像誘導下内視鏡手術システムの開発2013

    • Author(s)
      仲成幸
    • Organizer
      第41回日本磁気共鳴医学会大会
    • Place of Presentation
      徳島市
    • Year and Date
      20130919-21
  • [Presentation] 腹腔鏡下手術訓練のための,力覚提示システムの検討2013

    • Author(s)
      加藤十磨
    • Organizer
      第18回日本バーチャルリアリティ学会大会
    • Place of Presentation
      大阪市
    • Year and Date
      20130918-20
  • [Presentation] An MR image navigation system for a closed bore scanner with a needle insertion manipulator2013

    • Author(s)
      Morikawa S
    • Organizer
      9th Asian Conference on Computer Aided Surgery (ACCAS 2013)
    • Place of Presentation
      Tokyo. Best Paper Award
    • Year and Date
      20130916-18
  • [Presentation] 肝細胞癌に対するMR 画像誘導下マイクロ波凝固療法2013

    • Author(s)
      仲成幸
    • Organizer
      第32回Microwave Surgery 研究会
    • Place of Presentation
      東京都
    • Year and Date
      20130913-14
  • [Presentation] ^<1>H-MR イメージング用アレイコイルを利用した^<1>H 検出^<13>C-MR エコープラナースペクトロスコピックイメージングの試み2013

    • Author(s)
      森川茂廣
    • Organizer
      第16回NMR マイクロイメージング研究会
    • Place of Presentation
      大津市
    • Year and Date
      20130802-03
  • [Presentation] Current Status of Organ Variation 3D Model Library Construction2013

    • Author(s)
      Komori M
    • Organizer
      35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEEEMBC2013)
    • Place of Presentation
      Osaka
    • Year and Date
      20130703-07
  • [Presentation] A Semi-Automatic Modeling Approach for Serosa and Adhesion2013

    • Author(s)
      Tagawa K
    • Organizer
      35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE-EMBC 2013)
    • Place of Presentation
      Osaka
    • Year and Date
      20130703-07
  • [Presentation] MR 画像誘導によるSimulation/ Navigation Surgery2013

    • Author(s)
      仲成幸
    • Organizer
      第113回日本外科学会定期学術集
    • Place of Presentation
      福岡市
    • Year and Date
      20130411-13
  • [Presentation] Trainee's Action Archiving System for Supporting Laparoscopic Surgery Training2013

    • Author(s)
      Marutani T
    • Organizer
      International Conference on 3D Systems and Applications (3DSA2013)
    • Place of Presentation
      Osaka
    • Year and Date
      20130126-28
  • [Presentation] 腹腔鏡下手術訓練支援のためのデプスセンサおよび3次元力覚提示デバイスを用いた訓練者手技の観測・提示手法の検討2013

    • Author(s)
      丸谷宜史
    • Organizer
      第13回VR 医学会学術大会
    • Place of Presentation
      寝屋川市
    • Year and Date
      2013-08-31
  • [Presentation] Constructive Multi-Resolution Kodeling for Expressing Cysthepatic Duct Anomaly in a Laparoscopic Surgery Simulator2012

    • Author(s)
      Ohmi N
    • Organizer
      The 8th Joint Workshop on Machine Perception and Robotics (MPR2012)
    • Place of Presentation
      Fukuoka
    • Year and Date
      20121016-17
  • [Presentation] Seamless MR image navigation system using a motorized manipulator with optical and electromagnetic sensors for a closed bore scanner.2012

    • Author(s)
      Morikawa S
    • Organizer
      9th Interventional MRI Symposium
    • Place of Presentation
      Boston
    • Year and Date
      20120922-23
  • [Presentation] Technical Development of Endoscopic Surgery with Near Real- time MRI Guidance2012

    • Author(s)
      Haque HA
    • Organizer
      9th Interventional MRI Symposium
    • Place of Presentation
      Boston
    • Year and Date
      20120922-23
  • [Presentation] MR-Image Guided Endoscopic surgery - Initial Animal Study2012

    • Author(s)
      Naka S
    • Organizer
      9th Interventional MRI Symposium
    • Place of Presentation
      Boston
    • Year and Date
      20120922-23
  • [Presentation] 重畳映像力提示を用いる腹腔鏡下手術手技訓練システムの提案とその学習効果2012

    • Author(s)
      加藤十麿
    • Organizer
      第17回日本VR 学会
    • Place of Presentation
      横浜市
    • Year and Date
      20120912-14
  • [Presentation] MR画像誘導下内視鏡手術システムによる肝癌治療2012

    • Author(s)
      仲成幸
    • Organizer
      第48回日本肝癌研究会
    • Place of Presentation
      金沢市
    • Year and Date
      20120720-21
  • [Presentation] NOTES における新しい誘導システムの開発2012

    • Author(s)
      仲成幸
    • Organizer
      第67回日本消化器外科学会総会
    • Place of Presentation
      富山市
    • Year and Date
      20120718-20
  • [Presentation] MR 画像誘導下におけるGd-EOB-DTPA 造影MRI の有用性2012

    • Author(s)
      仲 成幸
    • Organizer
      第67回日本消化器外科学会総会
    • Place of Presentation
      富山市
    • Year and Date
      20120718-20
  • [Presentation] MR画像誘導下手術システムの開発 さらなる手術成績の向上と低侵襲性を求めて2012

    • Author(s)
      谷徹
    • Organizer
      第67回日本消化器外科学会総会
    • Place of Presentation
      富山市
    • Year and Date
      20120718-20
  • [Presentation] Expression of cystohepatic duct anomaly using modular structured organ model in a laparoscopic surgery simulator2012

    • Author(s)
      K. Tagawa
    • Organizer
      The 26th International Congress and Exhibition of Computer Assisted Radiology and Surgery (CARS 2012)
    • Place of Presentation
      Pisa, Italy
    • Year and Date
      20120627-30
  • [Presentation] MR-image guided surgical system for endoscopic surgery2012

    • Author(s)
      S. Naka
    • Organizer
      The 26th International Congress and Exhibition of Computer Assisted Radiology and Surgery (CARS 2012)
    • Place of Presentation
      Pisa, Italy
    • Year and Date
      20120627-30
  • [Presentation] Intraoperative MR Image Guided Endoscopic Surgery on a Closed Bore MR Scanner2012

    • Author(s)
      Haque HA
    • Organizer
      ISMRM 20th Annual Meeting & Exhibition
    • Place of Presentation
      Melbourne, Australia. (Second Place Poster Award in Interventional Study Group)
    • Year and Date
      20120505-11
  • [Presentation] MR画像誘導下手術システムの開発-汎用化を目指した取り組み2012

    • Author(s)
      仲成幸
    • Organizer
      第112回日本外科学会定期学術集会
    • Place of Presentation
      千葉
    • Year and Date
      20120412-14
  • [Presentation] MR画像誘導下手術システムによる肝癌治療2012

    • Author(s)
      仲成幸
    • Organizer
      日本消化器病学会近畿支部 第97回例会
    • Place of Presentation
      京都市
    • Year and Date
      2012-09-01
  • [Presentation] 臓器異型に対応した腹腔鏡手術シミュレータの構築2012

    • Author(s)
      田川和義
    • Organizer
      日本VR 医学会大会
    • Place of Presentation
      千葉
    • Year and Date
      2012-08-25
  • [Presentation] NOTES における画像誘導の有用性 -NOTES の適応拡大を目指した取り組みー2011

    • Author(s)
      仲成幸
    • Organizer
      第24回日本内視鏡外科学会総会
    • Place of Presentation
      大阪
    • Year and Date
      20111207-09
  • [Presentation] Development of cyber MR operating room for intraoperative MRI guided surgery2011

    • Author(s)
      Hasnine A Haque
    • Organizer
      第20回日本コンピュータ外科学会大会
    • Place of Presentation
      横浜
    • Year and Date
      20111122-24
  • [Presentation] ここまで出来るNOTES MR画像誘導によるNOTES の可能性2011

    • Author(s)
      仲成幸
    • Organizer
      第73回日本臨床外科学会総会
    • Place of Presentation
      東京都
    • Year and Date
      20111117-19
  • [Presentation] An efficient detachment simulation method using online re-mesh and rectangular tetrahedral volume mesh2011

    • Author(s)
      Tagawa K
    • Organizer
      Machine Perception and Robotics
    • Place of Presentation
      北京
    • Year and Date
      20111013-14
  • [Presentation] Image guided liver surgery using robot manipulator2011

    • Author(s)
      Naka S
    • Organizer
      第26回生体・生理工学シンポジウム
    • Place of Presentation
      草津市
    • Year and Date
      20110709-10
  • [Presentation] MR Image ガイド下肝腫瘍凝固療法におけるGd-EOB-DTPA の有用性2011

    • Author(s)
      仲成幸
    • Organizer
      第23回日本肝胆膵外科学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      20110608-10
  • [Presentation] MR 画像誘導下低侵襲治療の開発と臨床経験2011

    • Author(s)
      森川茂廣
    • Organizer
      第86回日本医療機器学会大会 (ワークショップ「先進治療機器の臨床経験と課題」招待)
    • Place of Presentation
      横浜市
    • Year and Date
      20110602-04
    • Invited
  • [Presentation] MR 画像ガイド手術における穿刺支援ロボットの臨床応用2011

    • Author(s)
      森川茂廣
    • Organizer
      第28回日本医学会総会(シンポジウム「ロボット医療」招待)
    • Place of Presentation
      Web 開催
    • Year and Date
      20110600
    • Invited
  • [Presentation] MRI ガイド手術のための穿刺軌道の計測2011

    • Author(s)
      森 厚郎
    • Organizer
      計測自動制御学会システムインテグレーション部門学術講演会
    • Place of Presentation
      京都
    • Year and Date
      2011-12-24
  • [Presentation] 腹腔鏡手術シミュレータのための臓器異型モデル構築2011

    • Author(s)
      小森優
    • Organizer
      第11回日本VR 医学会学術大会
    • Place of Presentation
      生駒市
    • Year and Date
      2011-08-27
  • [Book] MRI-Guided Microwave Ablation. In: Interventional Magnetic Resonance Imaging Kahn T, Busse H.(Eds.)2012

    • Author(s)
      Morikawa S, Naka S, Murayama H, kurumi Y, Tani T, Haque HA
    • Total Pages
      389-402
    • Publisher
      Splinger Berlin Heiderberg
  • [Book] Simultaneous Endoscopy and MRI Acquisition. In: Interventional Magnetic Resonance Imaging Kahn T, Busse H.(Eds.)2012

    • Author(s)
      Haque AH, Morikawa S, Naka S, Kurumi Y, Murayama H, Tani T, Tsukamoto T
    • Total Pages
      471-479
    • Publisher
      Splinger Berlin Heiderberg
  • [Patent(Industrial Property Rights)] 穿刺支援装置2014

    • Inventor(s)
      森川茂廣, 仲成幸, 山田篤史
    • Industrial Property Rights Holder
      滋賀医科大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      特願2014-30656
    • Filing Date
      2014-02-20

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Published: 2015-06-25  

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