Environmental pollutions and ecological effects of novel halogenated aromatic hydrocarbons

2013 Fiscal Year Final Research Report

• Project/Area Number: 23310011
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Environmental dynamic analysis
• Research Institution: Meijo University
• Principal Investigator: OHURA Takeshi 名城大学, 農学部, 准教授 (60315851)
• Co-Investigator(Kenkyū-buntansha): NIZUMA Yasuaki 名城大学, 農学部, 准教授 (00387763) ; SAKAKIBARA Hiroyuki 宮崎大学, 農学部, 准教授 (20403701) ; HORII Yuichi 埼玉県環境科学国際センター, 研究員 (30509534)
• Project Period (FY): 2011-04-01 – 2014-03-31
• Keywords: 塩素化PAHs / 臭素化PAHs / ハロゲン化PAHs / 環境動態 / 生体影響 / 多環芳香族炭化水素

Research Abstract

In the present study, we focused the halogenated polycyclic aromatic hydrocarbons (halogenated PAHs) that is one of non-regulated pollutants, and investigated the occurrences in the environment and the biological effects. The surveys of chlorinated PAHs (ClPAHs) ambient air in 14 sites in Japan, 1 site in Korea and 1 site in China showed that ClPAHs is universally present in the air since some of that were detected from all air samples. In addition, the surveys of ClPAHs in Asian sediments also showed the universalistic pollution. The biological effects were investigated by oral administration of ClPAH in rat, resulting that chlorination of PAH could enhance significantly induction of specific drug-metabolizing enzyme.

Research Products

• [Journal Article] Atmospheric chlorinated polycyclic aromatic hydrocarbons in East Asia (2014)
  • Author(s): K. Kakimoto, H. Nagayoshi, Y. Konishi, K. Kajimura, T. Ohura, K. Hayakawa, A. Toriba
  • Journal Title: Chemosphere Volume: 111 Pages: 40-46
  • DOI: 10.1016/j.chemosphere.2014.03.072
  • Peer Reviewed
• [Journal Article] Diurnal variability of chlorinated polycyclic aromatic hydrocarbons in urban air (2013)
  • Author(s): T. Ohura, M. Kojima, Y. Horii, Y. Kamiya
  • Journal Title: Japan. Atmos. Environ. Volume: 81 Pages: 84-91
  • DOI: 10.1016/j.atmosenv.2013.08.044
  • Peer Reviewed
• [Journal Article] Airborne PM2.5/PM10-associated chlorinated polycyclic aromatic hydrocarbons and their parent compounds in a suburban area in Shanghai (2013)
  • Author(s): J. Ma, Z. Chen, M. Wu, J. Feng, Y. Horii, T. Ohura, K. Kannan
  • Journal Title: China. Environ Sci Technol. Volume: 47 Pages: 7615-7623
  • DOI: 10.1021/es400338h
  • Peer Reviewed
• [Journal Article] Organ-specific distribution of 7-chlorinated benz[a]anthracene and regulation of selected cytochrome P450 genes in rats (2013)
  • Author(s): H. Sakakibara, T. Ohura, T. Kido, N. Yamanaka, N. Tanimura, K. Shimoi, K. S Guruge
  • Journal Title: J. Toxicol. Sci. Volume: 38 Pages: 137-143
  • DOI: 10.2131/jts.38.137
  • Peer Reviewed
• [Journal Article] Evaluation of chlorinated benz[a]anthracene on hepatic toxicity in rats and mutagenic activity in Salmonella typhimurium (2013)
  • Author(s): T. Kido, H. Sakakibara, T. Ohura, K. S. Guruge, M. Kojima, J. Hasegawa, T. Iwamura, N. Yamanaka, M. Sakaguchi, T. Amagai, K. Shimoi
  • Journal Title: Environ. Toxicol Volume: 28 Pages: 21-30
  • DOI: 10.1002/tox.20693
  • Peer Reviewed
• [Journal Article] Chlorinated Polycyclic Aromatic Hydrocarbons in Urban Surface Dust and Soil of Shanghai (2013)
  • Author(s): J. Ma, J. S. Zheng, Z. Y. Chen, M. H. Wu, Y. Horii, T. Ohura, K. Kannan
  • Journal Title: China. Advanced Materials Research Volume: 610-613 Pages: 2989-2994
  • DOI: 10.4028/www.scientific.net/AMR.610-613.2989
  • Peer Reviewed
• [Journal Article] Inhalation cancer risk associated with exposure to complex polycyclic aromatic hydrocarbon mixtures in an electronic waste and urban area in South China (2012)
  • Author(s): J. Wang, S-J. Chen, M. Tian, X. Zheng, L. Gonzales, T. Ohura, B. Mai, S. Simonich
  • Journal Title: Environ. Sci. Technol. Volume: 46 Pages: 9745-9752
  • DOI: 10.1021/es302272a
  • Peer Reviewed
• [Journal Article] Comprehensive two-dimensional gas chromatography coupled to high-resolution time-of-flight mass spectrometry for analysis of Cl-/Br-PAHs in environmental samples (2011)
  • Author(s): T. Ieda, N. Ochiai, T. Miyawaki, T. Ohura, Y. Horii
  • Journal Title: Organohalogen Compd. Volume: 73 Pages: 2155-2158
  • URL: http://www.dioxin20xx.org/pdfs/2011/4804.pdf
  • Peer Reviewed
• [Journal Article] Characteristics of halogenated polycyclic aromatic hydrocarbons in flue gas from waste incinerators (2011)
  • Author(s): Y. Horii, N. Ohtsuka, K. Minomo, K. Nojiri, T. Ohura, Y. Miyake, K. Kannan
  • Journal Title: Organohalogen Compd. Volume: 73 Pages: 108-111
  • URL: http://www.dioxin20xx.org/pdfs/2011/0314.pdf
  • Peer Reviewed
• [Journal Article] Comparison of polycyclic aromatic hydrocarbon pollution in Chinese and Japanese residential air (2011)
  • Author(s): H. Lu, T. Amagai, T. Ohura
  • Journal Title: J. Environ. Sci. Volume: 23 Pages: 1512-1517
  • Peer Reviewed
• [Journal Article] Global and selective detection of organohalogens in environmental samples by comprehensive two-dimentional gas chromatography-tandem mass spectrometry and high-resolution time-of-flight mass spectrometry (2011)
  • Author(s): S. Hashimoto, Y. Takazawa, A. Fushimi, K. Tanabe, Y. Shibata, T. Ieda, N. Ochiai, H. Kanda, T. Ohura, Q. Tao, S. E. Reichenbach
  • Journal Title: J. Chromatogr. A Volume: 1218 Pages: 3799-3810
  • DOI: 10.1016/j.chroma.2011.04.042
  • Peer Reviewed
• [Journal Article] Environmental analysis of chlorinated and brominated polycyclic aromatic hydrocarbons by comprehensive two-dimensional gas chromatography coupled to high-resolution time-of-flight mass spectrometry (2011)
  • Author(s): T. Ieda, N. Ochiai, T. Miyawaki, T. Ohura, Y. Horii
  • Journal Title: J. Chromatogr. A Volume: 1218 Pages: 3224-3232
  • DOI: 10.1016/j.chroma.2011.01.013
  • Peer Reviewed
• [Presentation] Size distribution and source apportionment of chlorinated polycyclic aromatic hydrocarbons in an urban air, Japan (2013)
  • Author(s): Y. Kamiya, T. Ohura
  • Organizer: 2013 International Symposium on Polycyclic Aromatic Compounds (ISPAC 2013) conference
  • Place of Presentation: Corvallis, OR, USA
  • Year and Date: 20130908-12
• [Presentation] The Analytical development of chlorinated polycyclic aromatic hydrocarbons used by ion trap GC/MS, and bioaccumulation of wild organisms (2013)
  • Author(s): R. Suzuki, T. Ohura
  • Organizer: 2013 International Symposium on Polycyclic Aromatic Compounds (ISPAC 2013) conference
  • Place of Presentation: Corvallis, OR, USA
  • Year and Date: 20130908-12
• [Presentation] Environmental factors affecting the concentrations of chlorinated polycyclic aromatic hydrocarbons associated with particulate matters (2013)
  • Author(s): Y. Kamiya, F. Ikemori, T. Ohura
  • Organizer: SETAC Europe 23rd Annual Meeting
  • Place of Presentation: Glasgow, UK
  • Year and Date: 20130512-16
• [Presentation] Organ-specific distribution of 7-chlorinated benz[a]anthracene and regulation of selected cytochrome P450 genes in rats (2013)
  • Author(s): T. Ohura, H. Sakakibara, T. Kido, N. Yamanaka, N. Tanimura, K. Shimoi, K.S. Guruge
  • Organizer: SETAC Europe 23rd Annual Meeting
  • Place of Presentation: Glasgow, UK
  • Year and Date: 20130512-16
• [Presentation] 名古屋市の大気浮遊粒子中における塩素化芳香族類の年間変動および粒径分布 (2013)
  • Author(s): 神谷優太, 大浦 健
  • Organizer: 都市大気のPM2.5 研究会
  • Place of Presentation: 名古屋
  • Year and Date: 20130300
• [Presentation] 都市大気エアロゾルにおける塩素化多環芳香族炭化水素類の粒径別分布 (2013)
  • Author(s): 神谷優太, 池盛文数, 飯島明宏, 奥田知明, 大浦 健
  • Organizer: 第30回エアロゾル科学・技術研究討論会
  • Place of Presentation: 京都
  • Year and Date: 2013-08-28
• [Presentation] イオントラップ型 GC/MS を用いた塩素化芳香族類分析法の開発ならびに生体試料へ䛾適応 (2013)
  • Author(s): 鈴木里奈, 神谷優太, 大浦 健
  • Organizer: 第22回環境化学討論
  • Place of Presentation: 府中, 東京
  • Year and Date: 2013-08-01
• [Presentation] 塩素化多環芳香族炭化水素類䛾全国大気調査 (2013)
  • Author(s): 大浦 健, 神谷優太, 須原 健, 池盛文数, 中島大介
  • Organizer: 第22回環境化学討論
  • Place of Presentation: 府中, 東京
  • Year and Date: 2013-08-01
• [Presentation] 都市大気における塩素化多環芳香族炭化水素類の環境動態ならびに発生源解析 (2013)
  • Author(s): 神谷優太, 池盛文数, 飯島明宏, 奥田知明, 大浦 健
  • Organizer: 第22回環境化学討論
  • Place of Presentation: 府中, 東京
  • Year and Date: 2013-07-31
• [Presentation] ヒト乳がん細胞を用いた環境水の汚染評価 (2012)
  • Author(s): 久留戸涼子, 山本彩季, 秋元 慧, 大浦健, 下位香代子
  • Organizer: 第15回環境ホルモン学会研究発表会
  • Place of Presentation: 東京
  • Year and Date: 20121200
• [Presentation] イオントラップGC/MSによる加熱食品中の塩素化多環芳香族類の分析 (2012)
  • Author(s): 大浦 健, 松尾光樹, 神谷優太, 三輪良
  • Organizer: 本分析化学会第61年会
  • Place of Presentation: 金沢
  • Year and Date: 20120900
• [Presentation] 飛行時間型GC/MSを用いる焼却排ガス中ハロゲン化芳香族群の検索 (2012)
  • Author(s): 堀井勇一, 野尻喜好, 大塚宜寿, 大浦 健, 三宅祐一
  • Organizer: 第21回環境化学討論会
  • Place of Presentation: 松山
  • Year and Date: 20120700
• [Presentation] 紫外線照射下における塩素化多環芳香族類の動態解析 (2012)
  • Author(s): 三輪 良, 大浦 健
  • Organizer: 日本化学会第92春季年会
  • Place of Presentation: 神奈川
  • Year and Date: 20120300
• [Presentation] GC/QMSによる塩素化多環芳香族炭化水素類の高感度分析法の開発及び環境分析への適用 (2012)
  • Author(s): 神谷優太, 大浦 健
  • Organizer: 日本化学会第92春季年会
  • Place of Presentation: 神奈川
  • Year and Date: 20120300
• [Presentation] Screening of novel halogenated aromatic hydrocarbons in environmental samples by GC coupled to high resolution TOFMS (2012)
  • Author(s): Y. Horii, K. Nojiri, N. Yamashita, K. Kannan, T. Ohura, Y. Miyake
  • Organizer: SETAC North America 33rd Annual Meeting
  • Place of Presentation: CA, USA
  • Year and Date: 2012-11-12
• [Presentation] Chlorinated polycyclic aromatic hydrocarbons in urban surface dust and soil of Shanghai, China (2012)
  • Author(s): J. Ma, J. Zheng, Z. Chen, M. Wu, Y. Horii, T. Ohura, K. Kannan
  • Organizer: SETAC North America 33rd Annual Meeting
  • Place of Presentation: CA, USA
  • Year and Date: 2012-11-12
• [Presentation] 多環芳香族炭化水素及びそのハロゲン置換体の乳がん細胞に及ぼす影響 (2011)
  • Author(s): 久留戸涼子, 山本彩季, 大浦 健, 榊原啓之, 下位香代子
  • Organizer: 第14回環境ホルモン学会研究発表会
  • Place of Presentation: 東京
  • Year and Date: 20111200
• [Presentation] Halogenated polycyclic aromatic hydrocarbons in urban air from Albany, USA (2011)
  • Author(s): Y. Horii, B. Johson, T. Ohura, K. Kannan
  • Organizer: SETAC North America, 32nd Annual Meeting
  • Place of Presentation: Boston, MA
  • Year and Date: 20111113-17
• [Presentation] Diurnal variation of chlorinated polycyclic aromatic hydrocarbons in urban air, Japan (2011)
  • Author(s): T. Ohura, M. Kojima, Y. Horii
  • Organizer: The 23rd International Symposium on Polycyclic Aromatic Compounds
  • Place of Presentation: Münster, Germany
  • Year and Date: 20110904-08
• [Presentation] GC x GC-高分解能TOF-MSによる塩素化・臭素化PAHsの分析その2-負イオン化学イオン化法の適用- (2011)
  • Author(s): 家田曜世, 落合伸夫, 宮脇俊文, 堀井勇一, 大浦 健
  • Organizer: 第20回環境化学討論会
  • Place of Presentation: 熊本
  • Year and Date: 20110700
• [Presentation] Characteristics of halogenated polycyclic aromatic hydrocarbons in flue gas from waste incinerators
  • Author(s): Horii Y, Ohtsuka N, Minomo K, Nojiri K, Ohura T, Miyake Y, Kannan K
  • Organizer: 31st International Symposium on Halogenated Persistent Organic Pollutants POPs' Science in the Heart of Europe
  • Place of Presentation: Brussels, Belgium
  • Year and Date: 00000821-25
• [Presentation] Comprehensive two-dimensional gas chromatography coupled to high-resolution time-of-flight mass spectrometry for analysis of Cl-/Br-PAHs in environmental samples
  • Author(s): Ieda T, Ochiai N, Miyawaki T, Ohura T, Horii Y
  • Organizer: 31st International Symposium on Halogenated Persistent Organic Pollutants POPs' Science in the Heart of Europe
  • Place of Presentation: Brussels, Belgium
  • Year and Date: 00000821-25
• [Book] Halogenated polycyclic aromatic hydrocarbons contamination in urban soils, an assessment of possible sources, In Green Materials for Energy, Products and Depollution (Eric Lichtfouse, Jan Schwarzbauer, Didier Robert, Eds.) (2013)
  • Author(s): T. Ohura, T. Yamamoto, K. Higashino, Y. Sasaki
  • Total Pages: 449-466
• [Book] Analysis of Halogenated Polycyclic Aromatic Hydrocarbons in the Air, In Air Quality- New Perspective (Gustavo Lopez, Benjamin Valdez, Michael Schorr, Eds.) (2012)
  • Author(s): T. Ohura, Y. Kamiya, F. Ikemori, T. Imanaka, M. Ando
  • Total Pages: 313-326