Design of Molecular Catalyst using Alkyl Chain as a Functional Group

2014 Fiscal Year Final Research Report

• Project/Area Number: 23350017
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Synthetic chemistry
• Research Institution: Kyoto University
• Principal Investigator: MATSUBARA Seijiro 京都大学, 工学(系)研究科(研究院), 教授 (90190496)
• Project Period (FY): 2011-04-01 – 2015-03-31
• Keywords: 複素環合成 / 有機分子触媒 / 金属ポルフィリン / ニッケル触媒 / 有機亜鉛

Outline of Final Research Achievements

At the beginning of the project, we focused on the alkyl chain, which has a self-assembling ability and hydrophobicity, and tried to develop highly selective and efficient catalyst. During the research, we found a use of organocatalyst, which has a molecular flame with two functional group, is effective for the preparation of heterocyclic compound with high asymmetric induction. Moreover, we also found a novel cycloaddition reaction using metal-porphiryn catalyst, which has high hydrophobicity. And also, we developed novel method for the preparation of cyclic compounds using nickel catalyst and organozinc reagent.

Free Research Field

有機合成化学