2013 Fiscal Year Final Research Report
Design of High Performance Catalysts Based on Biomimetic Approach
Project/Area Number |
23350039
|
Research Category |
Grant-in-Aid for Scientific Research (B)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Synthetic chemistry
|
Research Institution | Okayama University (2012-2013) Nagoya University (2011) |
Principal Investigator |
SAKAKURA Akira 岡山大学, 自然科学研究科, 教授 (80334043)
|
Project Period (FY) |
2011-04-01 – 2014-03-31
|
Keywords | 触媒設計・反応 |
Research Abstract |
Based on acid-base combination chemistry, we conducted the rational design of high performance catalysts with functionalities such as weak secondary interaction and acid-base dual activation. Using these catalysts, we developed highly selective synthetic processes. For example, we achieved dehydrative ester condensation in water using organoammonium catalysts, enantioselective carbon-carbon bond forming reactions (Diels-Alder reaction, polyene cyclization and iodolactonization of unsaturated carboxylic acids) and acylation reaction based on acid-base combination catalysis (cyanoethoxycarbonylation of isatins and dehydrative amide condensation of alpha-hydroxy carboxylic acids).
|
Research Products
(60 results)