2013 Fiscal Year Final Research Report
Elucidation of Interfacial Structure and Functionality of the Biomembrane on the ECM
| Project/Area Number |
23350058
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Functional materials chemistry
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| Research Institution | Hokkaido University |
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Principal Investigator |
YE Shen 北海道大学, 触媒化学研究センター, 准教授 (40250419)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Keywords | 界面分子構造 / 細胞膜 / 細胞外基質(ECM) / 生体適合性材料 / 和周波発生(SFG) / ポリロタキサン / 高分子電解質 / タンパク質分子 |
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| Research Abstract |
The surface of cell membrane is typically covered by the extracellular matrix (ECM), which controls the local environment of the cell membrane surface and strongly affects functionality of the cell membrane. However, a number of issues related to the relationship of the structure and functionality of ECM are still unclear. In the present study, to understand the functionality of the ECM, the interfacial molecule structures of a series of biocompatible materials which could be employed as ECM, such as polyrotaxane supramolecules with cyclodextrin hosts, polymer electrolyte and cationic surfactant molecules, have been characterized by the sum frequency generation (SFG) vibrational spectroscopy and atomic force microscope (AFM) at a molecular level. The information obtained is useful to understand the functionality of ECM by controlling their interfacial structures.
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Research Products
(45 results)
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[Journal Article] Effect of Functional Group on the Monolayer Structures of Biodegradable Quaternary Ammonium Surfactants2013
Author(s)
Ge, A.; Peng, Q.; Wu, H.; Liu, H.; Tong, Y.; Nishida, T.; Yoshida, N.; Suzuki, K.; Sakai, T.; Osawa, M.; Ye, S.
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Journal Title
Langmuir
Volume: 29
Pages: 14411-14420
Peer Reviewed
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[Journal Article] Role of Adsorption Structures of Zn-Porphyrin on TiO2 in Dye-Sensitized Solar Cells Studied by Sum Frequency Generation Vibrational Spectroscopy and Ultrafast Spectroscopy2013
Author(s)
Ye, S. ; Kathiravan, A.; Hayashi, H.; Tong, Y.; Infahsaeng, Y.; Chabera, P.; Pascher, T.; Yartsev, A.; Isoda, S.; Imahori, H.; Sundström, V
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Journal Title
J. Phys. Chem. C
Volume: 117
Pages: 6066-6080
Peer Reviewed
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