2013 Fiscal Year Final Research Report
Evolution of Eye as sensory organ
Project/Area Number |
23370098
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Evolutionary biology
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Research Institution | National Institute of Genetics |
Principal Investigator |
IKEO KAZUHO 国立遺伝学研究所, 生命情報研究センター, 准教授 (20249949)
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Project Period (FY) |
2011-04-01 – 2014-03-31
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Keywords | 分子進化 |
Research Abstract |
To understand the process and origin of various eyes, I conducted comparative evolutionary study by using next generation sequence technology. For the purpose, I took two different types of Jellyfish with and without eye and also dinoflagellate with different types of lens eye. RNA-seq by next generation sequence technology performed collection of gene expression profiles of the species. The visual pigment of dinoflagellate showed the similarity with bacterial pigment and it suggests the origin of their eye-like structure related to bacterial origin. The other side, the result of jellyfish showed the molecules related their lens development evolutionaliry related with our genes, thus, jellyfish already gain molecular system for lens conformation before establishing nervous system. Now, we still continue more fine analysis of the data.
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[Journal Article] Comparison of gene expression profile of epiretinal membranes obtained from eyes with proliferative vitreoretinopathy to that of secondary epiretinal membranes2013
Author(s)
Asato R, Yoshida S, Ogura A, Nakama T, Ishikawa K, Nakao S, Sassa Y, Enaida H, Oshima Y, Ikeo K, Gojobori T, Kono T, Ishibashi T
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Journal Title
PLoS One
Volume: 8(1)
Pages: e54191
Peer Reviewed