Identification of food component which selectively inhibits abnormal vascular contraction

2014 Fiscal Year Final Research Report

• Project/Area Number: 23380077
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Food science
• Research Institution: Yamaguchi University
• Principal Investigator: KOBAYASHI Sei 山口大学, 医学(系)研究科(研究院), 教授 (80225515)
• Co-Investigator(Kenkyū-buntansha): KISHI Hiroko 山口大学, 大学院医学系研究科, 准教授 (40359899) ; KAJIYA Katsuko 鹿児島大学, 農学部, 講師 (00379942) ; ZHANG Ying 山口大学, 大学院医学系研究科, 助教 (10711260)
• Project Period (FY): 2011-04-01 – 2015-03-31
• Keywords: 病態生理 / 血管攣縮 / 血管異常収縮 / 血管病 / 機能性食品

Outline of Final Research Achievements

The purpose of this study is to clarify the molecular mechanism of abnormal vascular contraction and to identify the food component which selectively inhibit abnormal vascular contraction without affecting the normal contraction.
In this study, we identified the novel signal mediator mediating between Fyn tyrosine kinase and Rho-kinase in the regulation of abnormal vascular contractions.
We identified the food component which selectively inhibit abnormal vascular contraction without affecting the normal contraction. By these results we applied two patents.

Free Research Field

分子細胞生理学