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2013 Fiscal Year Final Research Report

Visceral adiposity and cardiometabolic diseases in Japanese: the phase 1 follow-up examination

Research Project

  • PDF
Project/Area Number 23390177
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Public health/Health science
Research InstitutionOsaka City University

Principal Investigator

HAYASHI TOMOSHIGE  大阪市立大学, 医学(系)研究科(研究院), 准教授 (10381980)

Co-Investigator(Kenkyū-buntansha) SATO Kyoko  大阪市立大学, 大学院・医学研究科, 講師 (00381989)
ENDO Ginji  大阪市立大学, 大学院・医学研究科, 教授 (20160393)
Project Period (FY) 2011-04-01 – 2014-03-31
Keywords内臓脂肪 / 疫学 / 生活習慣病 / 日系人
Research Abstract

We had enrolled 1649 subjects between 2005 and 2010 to examine the association between visceral adiposity and fat liver measured by computed tomography (CT), and the risk of future lifestyle-related diseases.
Intraclass correlation coefficients for intra- and inter-reader comparisons of the measurement of fatty liver showed a good reliability. In the prospective analyses, visceral adiposity was associated with an increased risk of the future type 2 diabetes, hypertension, hypertriglycerides, and low high-density lipoprotein (HDL) cholesterol independent of fatty liver, age, and gender. On the other hand, fatty liver was associated with an increased risk of the future type 2 diabetes and low HDL cholesterol, not hypertension or hypertriglycerides, independent of visceral fat, age, and gender.

  • Research Products

    (13 results)

All 2014 2013 2012 2011

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (9 results) (of which Invited: 1 results) Book (2 results)

  • [Journal Article] Patterns of Insulin Concentration During the OGTT Predict the Risk of Type 2 Diabetes in Japanese Americans2013

    • Author(s)
      Tomoshige Hayashi, Edward J. Boyko, Kyoko Kogawa Sato, Marguerite J. McNeely, Donna L. Leonetti, Steven E. Kahn, Wilfred Y. Fujimoto
    • Journal Title

      Diabetes Care

      Volume: 36巻 Pages: 1229-1235

    • Peer Reviewed
  • [Journal Article] Risk Factors for Type 2 Diabetes : Lessons Learned from Japanese Americans in Seattle2012

    • Author(s)
      Wilfred Y. Fujimoto, Edward J. Boyko, Tomoshige Hayashi, Steven E Kahn, Donna L Leonetti, Marguerite J McNeely, William P Shuman
    • Journal Title

      J Diabetes Investig

      Volume: 3巻 Pages: 212-224

    • Peer Reviewed
  • [Presentation] Japanese Americans Community Diabetes study-シアトル日系人糖尿病研究の知見から2014

    • Author(s)
      林朝茂
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪国際会議場, 大阪
    • Year and Date
      20140522-24
    • Invited
  • [Presentation] Using Category-free Net Reclassification Improvement and Integrated Discrimination Improvement to Assess Which Insulin Sensitivity Index Best Predicts Type 2 Diabetes2013

    • Author(s)
      Kyoko Sato
    • Organizer
      The 13th International Diabetes Epidemiology Group Symposium
    • Place of Presentation
      Baker IDI Heart and Diabetes Institute, Melbourne, Australia
    • Year and Date
      20131130-1202
  • [Presentation] Predicting Incident Type 2 Diabetes by Insulin Sensitivity Index using Reclassification2013

    • Author(s)
      Yukiko Onishi
    • Organizer
      73rd American Diabetes Association's Scientific Sessions
    • Place of Presentation
      McCormick Place Convention Center, Chicago, USA
    • Year and Date
      20130621-25
  • [Presentation] Visceral adiposity, not abdominal subcutaneous fat area, is associated with glucose intolerance in Japanese : the Ohtori study2012

    • Author(s)
      Hideaki Sokooshi
    • Organizer
      The 9th International Diabetes Federation Western Pacific Region Congress, The 4th Scientific Meeting of the Asian Association for the Study of Diabetes
    • Place of Presentation
      京都国際会議場, 京都
    • Year and Date
      20121124-27
  • [Presentation] Apo A-1 and Apo B in Association with Abdominal Visceral Adiposity and Ectopic Fat Depots2012

    • Author(s)
      Sato Kyoko
    • Organizer
      72nd American Diabetes Association's Scientific Sessions
    • Place of Presentation
      Pennsylvania Convention Center, Philadelphia, USA
    • Year and Date
      20120608-12
  • [Presentation] Higher Total and VLDL Triglycerides and Lower HDL Cholesterol, but Not LDL Cholesterol, Predict Future Visceral Adiposity in Nondiabetic Japanese Americans2012

    • Author(s)
      Tomoshige Hayashi
    • Organizer
      72nd American Diabetes Association's Scientific Sessions
    • Place of Presentation
      Pennsylvania Convention Center, Philadelphia, USA
    • Year and Date
      20120608-12
  • [Presentation] 腹部内臓脂肪と高血圧の関連2012

    • Author(s)
      疋田米造
    • Place of Presentation
      東京国際フォーラム, 東京
    • Year and Date
      2012-01-21
  • [Presentation] Thigh Muscle CT Attenuation Is Associated with Insulin Resistance Independent of Visceral Adiposity and Fatty Liver2011

    • Author(s)
      Isseki Maeda
    • Organizer
      American Diabetes Association 71th Scientific Sessions
    • Place of Presentation
      San Diego Convention Center, San Diego, USA
    • Year and Date
      20110624-28
  • [Presentation] Late Phase Insulin Resistance and Secretion during the OGTT Independently Predict the Risk of Type 2 Diabetes2011

    • Author(s)
      Tomoshige Hayashi
    • Organizer
      American Diabetes Association 71th Scientific Sessions
    • Place of Presentation
      San Diego Convention Center, San Diego, USA
    • Year and Date
      20110624-28
  • [Book] 糖尿病学の進歩2011: 糖尿病診療に必要な知識 The Seattle Japanese Americans Community Diabetes Study より2011

    • Author(s)
      林 朝茂
    • Total Pages
      8-11
    • Publisher
      診断と治療社
  • [Book] メタボリックシンドロームと血管病変に関する最近の疫学2011

    • Author(s)
      林朝茂
    • Total Pages
      1-3
    • Publisher
      医事出版社

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Published: 2015-06-25  

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