2013 Fiscal Year Final Research Report
Neuroimaging study for exploring remaining cortical function of aphasic patients
| Project/Area Number |
23390354
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Cerebral neurosurgery
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| Research Institution | Jichi Medical University |
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Principal Investigator |
WATANABE Eiju 自治医科大学, 医学部, 教授 (50150272)
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| Co-Investigator(Kenkyū-buntansha) |
DAN Ippeita 自治医科大学, 医学部, 准教授 (20399380)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Keywords | 失語症 / 脳機能 / 脳機能イメージング / テーラーメイド医療 / 光トポグラフィー / 言語処理 |
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| Research Abstract |
The current study explored the remaining cortical function of aphasic patients using functional neuroimaging technique exemplified as optical topography. Among two major language tasks, namely, naming and verbal fluency tasks, which have seemed suitable for this purpose, we verified that the naming task had clearer laterality with large enough signal amplitudes. Optical topography analyses on aphasic patients at sub-acute phase revealed that activation of the left Wernicke area might be a typical neural signature to represent compensational cortical activation for the dysfunction of the Broca area.
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Research Products
(44 results)
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[Journal Article] Neuropharmacological effect of methylphenidate on attention network in children with attention deficit/hyperactivity disorder during oddball paradigms as assessed using fNIRS2014
Author(s)
Nagashima, M., Dan, I., Monden, Y., Dan, H.,, Tsuzuki, D., Mizutani, T., Kyutoku, Y., Gunji, Y., Momoi, M. Y., Watanabe, E., Yamagata, T
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Journal Title
Neurophotonics
Volume: (in press)
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[Journal Article] Referential framework for transcranial anatomical correspondence for fNIRS based on manually traced sulci and gyri of an infant brain2014
Author(s)
Matsui, M., Homae, F., Tsuzuki, D., Watanabe, H. Katagiri, M., Uda, S., Nakashima, M., Dan, I., Taga, G
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Journal Title
Neuroscience Research
Volume: 80
Pages: 55-68
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[Journal Article] Direct cortical hemodynamics mapping of somatotopy of pig nostril sensation by functional Near-infrared Cortical Imaging (fNCI)2014
Author(s)
Uga, M., Saito, T., Sano, T., Yokota, H., Oguro, K., Rizki, E.E., Mizutani, T., Katura, T., Dan, I., Watanabe, E
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Journal Title
NeuroImage
Volume: 91
Pages: 138-145
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[Journal Article] Effect of auditory input on activations in infant diverse cortical regions during audiovisual processing2013
Author(s)
Watanabe, H., Homae, F., Nakano, T., Tsuzuki, D., Enkhtur, L., Nemoto, K., Dan, I., and Taga, G
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Journal Title
Human Brain Mapping
Volume: 34(3)
Pages: 543-565
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[Journal Article] Language-specific cortical activation patterns for verbal fluency tasks in Japanese as assessed by multichannel functional near-infrared spectroscopy2013
Author(s)
Dan, H., Dan, I., Sano, T., Kyutoku. Y., Oguro. K., Yokota, H., Tsuzuki, D., Watanabe, E
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Journal Title
Brain and Language
Volume: 126
Pages: 208-216
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[Journal Article] Acute moderate exercise enhances compensatory brain activation in older adults2012
Author(s)
Hyodo, K., Dan, I., Suwabe, K., Kyutoku, Y., Yamada, Y., Akahori, M., Byun, K., Kato, M., Soya, H
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Journal Title
Neurobiology of Aging
Volume: 33(11)
Pages: 2621-32
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[Journal Article] Stable and convenient spatial registration of stand-alone NIRS data through anchor-based probabilistic registration2012
Author(s)
Tsuzuki, D., Cai, D. S., Dan, H., Kyutoku, Y., Fujita, A., Watanabe, E. and Dan, I
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Journal Title
Neuroscience Research
Volume: 72(2)
Pages: 163-71
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[Journal Article] Multichannel fNIRS assessment of overt and covert confrontation naming2012
Author(s)
Moriai-Izawa, A., Dan, H., Dan, I., Sano, T., Oguro, K., Yokota, H., Tsuzuki, D., Watanabe, E
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Journal Title
Brain and Language
Volume: 121(3)
Pages: 185-93
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[Journal Article] Effect of anesthesia on trigeminal somatosensory evoked magnetic fields2012
Author(s)
Otsuka, T., Dan, H., Dan, I., Sase, M., Sano, T., Tsuzuki, D., Sasaguri, K., Okada, N., Kusama, M., Jinbu, Y., Watanabe, E
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Journal Title
J Dental Res
Volume: 91(12)
Pages: 1196-201
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[Journal Article] Right prefrontal activation as a neuro-functional biomarker for monitoring acute effects of methylphenidate in ADHD children : An fNIRS study2012
Author(s)
Monden, Y., Dan, H., Nagashima, M., Dan, I., Tsuzuki, D., Kyutoku, Y., Gunji, Y., Yamagata, T., Watanabe, E., Momoi, M.Y
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Journal Title
NuroImage : Clinical
Volume: 1(1)
Pages: 131-140
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[Journal Article] Validating atlas-guided DOT : a comparison of diffuse optical tomography informed by atlas and subject-specific anatomies2012
Author(s)
Cooper, R. J., Caffini, M., Dubb, J., Custo, A., Tsuzuki, D., Fischl, B., Wells, W. III, Dan, I., Boas, D. A
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Journal Title
NeuroImage
Volume: 62(3)
Pages: 1999-2006
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