2013 Fiscal Year Final Research Report
A Development of automated medical drug delivery system to support management of circulation, coupled with a neural treatment
| Project/Area Number |
23390415
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Emergency medicine
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| Research Institution | National Cardiovascular Center Research Institute |
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Principal Investigator |
KAMIYA ATSUNORI 独立行政法人国立循環器病研究センター, 研究所, 研究員 (30324370)
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| Co-Investigator(Kenkyū-buntansha) |
SUGIMACHI Masaru 独立行政法人国立循環器病研究センター研究所, 部長 (40250261)
KAWADA Toru 独立行政法人国立循環器病研究センター研究所, 室長 (30243752)
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| Project Period (FY) |
2011-04-01 – 2014-03-31
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| Keywords | 集中治療医学 |
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| Research Abstract |
Management of circulation in intensive care medicine is a highly specialized medical treatment, that directly determines vital prognosis of patients. Recently, however, a lack of physician decreases a medical care, while a great physical stress of physician leads human errors, as widely recognized as a social problem. The present study is a challenge to resolve the problem by creating automated medical system based on physiology, biomedical engineering and technology. It developed the automated medical system, in which a computer makes a diagnosis about cardiovascular dynamics, delivers multiple drugs simultaneously and improved cardiovascular dynamics, with emphasizing on a prediction of left atrial pressure, a fail-safe device, an alerm and an neural treatment.
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[Journal Article] Medetomidine, an α2-adrenergic agonist, activates cardiac vagal nerve through modulating baroreflex control2012
Author(s)
Shimizu S, Akiyama T, Kawada T, Sata Y, Mizuno M, Kamiya A, Shishido T, Inagaki M, Shirai M, Sano S, Sugimachi M
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Journal Title
Circ J
Volume: 76(1)
Pages: 152-9
Peer Reviewed
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[Journal Article] Centrally administered ghrelin activates cardiac vagal nerve in anesthetized rabbits2011
Author(s)
Shimizu S, Akiyama T, Kawada T, Sonobe T, Kamiya A, Shishido T, Tokudome T, Hosoda H, Shirai M, Kangawa K, Sugimachi M
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Journal Title
Auton Neurosci
Volume: 162(1-2)
Pages: 60-5
Peer Reviewed
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