Surveillance study tracking the changing nature of influenza viruses derived from domestic animals and birds in Egypt and Thailand

2015 Fiscal Year Final Research Report

• Project/Area Number: 23406017
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 海外学術
• Research Field: Laboratory medicine
• Research Institution: Osaka University
• Principal Investigator: Ikuta Kazuyoshi 大阪大学, 医学(系)研究科(研究院), 招へい教授 (60127181)
• Co-Investigator(Kenkyū-buntansha): WATANABE Yohei 京都府立医科大学, 医学研究科, 講師 (50452462) ; NAKAYA Takaaki 京都府立医科大学, 医学研究科, 教授 (80271633) ; SUZUKI Yasuo 中部大学, 生命健康科学部, 教授 (00046278) ; TAKAHASHI Kazuo 大阪府立公衆衛生研究所, 感染症部, 部長 (10171472)
• Co-Investigator(Renkei-kenkyūsha): DAIDOJI Tomo 京都府立医科大学, 医学研究科, 講師 (80432433)
• Research Collaborator: Ibrahim Madiha S. ダマンフール大学, 獣医学部, 教授
• Project Period (FY): 2011-04-01 – 2016-03-31
• Keywords: ウイルス学 / インフルエンザ / 人獣共通感染症 / 検査 / 国際研究者交流 / エジプト

Outline of Final Research Achievements

H5N1 highly pathogenic avian influenza viruses have become endemic in birds in Southeast Aria and Egypt. In particular, Egypt has a substantially　higher　prevalence　of　H5N1　viruses　than　any　other　country,　with　collateral　human infection. In this study, we developed a novel immunochromatographic strip test to detect influenza virus receptor binding specificity. Using the easy-to-use detection system, we surveyed the H5N1 virus dissemination and evolutionary dynamics in the H5N1 endemic areas. The results showed that a novel H5N1 virus variant with enhanced infectivity toward humans had emerged in Egypt and is now dominant in the country.

Free Research Field

ウイルス学