2013 Fiscal Year Final Research Report
Roles of scaffold protein JSAP in axonal transport
| Project/Area Number |
23500385
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Neuroscience in general
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2013
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| Keywords | シグナル伝達 / 足場タンパク質 / MAPキナーゼ / マウス / 軸索 / JNK / 神経 / 神経変性 |
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| Research Abstract |
Axonal transport is essential for neuronal development and function, and disrupted axonal transport is an important pathophysiological factor in a variety of neurodegenerative diseases. We suggest that scaffold protein JSAP may function as a positive regulator of kinesin-dependent axonal transport to prevent neuronal degeneration.
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[Journal Article] Displays of paternal mouse pup retrieval following communicative interaction with maternal mates2013
Author(s)
Liu HX, Lopatina O, Higashida C, Fujimoto H, Akther S, Inzhutova A, Liang M, Zhong J, Tsuji T, Yoshihara T, Sumi K, Ishiyama M, Ma WJ, Ozaki M, Yagitani S, Yokoyama S, Mukaida N, Sakurai T, Hori O, Yoshioka K, Hirao A, Kato Y, Ishihara K, Kato I, Okamoto H, Cherepanov SM, Salmina AB, Hirai H, Asano M, Brown DA, Nagano I, Higashida H
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Journal Title
Nat. Commun
Volume: 4
Pages: 1346
Peer Reviewed
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