2013 Fiscal Year Final Research Report
Central neuromodulators and decision making
| Project/Area Number |
23500393
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Neuroscience in general
|
|---|
| Research Institution | Fukushima Medical University |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2011 – 2013
|
| Keywords | ドパミン / アセチルコリン / 報酬 / 空間性注意 / 意思決定 |
|---|
| Research Abstract |
Motivation and attention play an important role in flexible and efficient decision making. We investigated the effects of dopaminergic and acetylcholinergic drugs on the performance of visual discrimination. In control subjects, l-dopa and donepezil both improved performance of visual discrimination. In right brain damage patients, left hemispatial neglect was ameliorated by both l-dopa and donepezil. The results suggest that both dopaminergic and acetylcholinergic systems are involved in visual processing.
|
