2013 Fiscal Year Final Research Report
Structural basis for dopaminergic regulation of odor information in the olfactory bulb glomeruli
| Project/Area Number |
23500419
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Nerve anatomy/Neuropathology
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| Research Institution | Kawasaki Medical School |
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Principal Investigator |
KIYOKAGE EMI 川崎医科大学, 医学部, 講師 (30543392)
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| Co-Investigator(Renkei-kenkyūsha) |
TOIDA Kazunori 川崎医科大学, 解剖学, 教授 (40253405)
KANEKO Takeshi 京都大学, 高次脳形態学, 教授 (90177519)
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| Project Period (FY) |
2011 – 2013
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| Keywords | ＴＨ / 嗅球 / 糸球体 / 介在ニューロン / シナプス / ３次元再構築 / 電子顕微鏡 |
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| Research Abstract |
Glomeruli are the initial site of synaptic integration in the olfactory pathway. Each glomerulus acts on the modulation of odor information inputs as a functional unit. We focus on tyrosine hydroxylase (TH) neurons that constitute glomeruli, and performed quantitative analysis of synapses TH neurons formed using correlative observation of immunoreactivity in confocal laser-scanning microscopy and transmission electron microscopy. Analysis of special distribution of synapses on TH neuron improves to understand the neural circuit for regulation of odor information.
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[Journal Article] Molecular Identity of Periglomerular and Short Axon Cells2010
Author(s)
Kiyokage E., Pan Y., Shao Z., Kobayashi K., Szabo G., Yanagawa Y., Obata K., Okano H., Toida K., Puche C.A., and Shipley T.M
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Journal Title
Journal of Neuroscience
Volume: 30(3)
Pages: 1185-1196
DOI
Peer Reviewed
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