Web-based brain atlas of the common marmoset

2013 Fiscal Year Final Research Report

• Project/Area Number: 23500423
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Nerve anatomy/Neuropathology
• Research Institution: Tokyo Metropolitan Institute of Medical Science
• Principal Investigator: TOKUNO Hironobu 公益財団法人東京都医学総合研究所, 認知症・高次脳機能研究分野, 副参事研究員 (40212071)
• Co-Investigator(Kenkyū-buntansha): TANAKA Ikuko 公益財団法人東京都医学総合研究所, 認知症・高次脳機能研究分野, 研究員 (60142650)
• Project Period (FY): 2011 – 2013
• Keywords: コモンマーモセット / 脳 / アトラス / トランスポーター / 免疫組織化学 / バーチャルマイクロスコピー / インターネット / データベース

Research Abstract

We have established brain and spinal cord web atlas of the common marmoset. This Internet-based database is available from all over the world (http://marmoset-brain.org) . We have zoomable histological images of adult brains, adult spinal cord, and brains of postnatal day 0 on the database. Additionally, we have images of sugar glider brain and spinal cords of Rhesus and Japanese macaques. Used staining methods are Nissl, AChE histochemistry, immunostaining of various calcium binding proteins, NeuN, neurotransmitter transporters. The total numbers of sections is now about 3900, which correspond to 290GB in data size. Two atlas books have been published based on our image database.

Research Products

• [Journal Article] ニューロサイエンスの最新情報 デジタル脳アトラスの現状と可能性 (2013)
  • Author(s): 徳野博信
  • Journal Title: Clin Neurosci Volume: 31(9) Pages: 1104-1105
  • Peer Reviewed
• [Journal Article] Experimental techniques for neuroscience research using common marmosets (2012)
  • Author(s): Tokuno H, Moriya-Ito K, Tanaka I
  • Journal Title: Exp Anim Volume: 61(4) Pages: 389-397
  • Peer Reviewed
• [Journal Article] Decision making and risk attitude of the common marmoset in a gambling task (2011)
  • Author(s): Tokuno H, Tanaka I
  • Journal Title: Neurosci Res Volume: 71(3) Pages: 260-265
  • Peer Reviewed
• [Journal Article] Effects of constant daylight exposure during early development on marmoset psychosocial behavior (2011)
  • Author(s): Senoo A, Okuya T, Sugiura Y, Mimura K, Honda Y, Tanaka I, Kodama T, Tokuno H, Yui K, Nakamura S, Usui S, Koshiba M
  • Journal Title: Prog Neuropsychopharmacol Biol Psychiatry Volume: 35(6) Pages: 1493-1498
  • Peer Reviewed
• [Journal Article] Internet-based atlas of the primate spinal cord (2011)
  • Author(s): Tokuno H, Tanaka I, Senoo A, Umitsu Y, Akazawa T, Nakamura Y, Watson C
  • Journal Title: Neurosci Res Volume: 70(1) Pages: 128-132
  • Peer Reviewed
• [Presentation] Introduction (2013)
  • Author(s): Hironobu Tokuno
  • Organizer: The 6th Igakuken International Symposium on Marmoset Neuroscience
  • Place of Presentation: Tokyo
  • Year and Date: 2013-10-03
• [Presentation] コモンマーモセット嗅球の構造 (2013)
  • Author(s): 徳野博信, 守屋敬子, 田中いく子, 海津敬倫, 市川眞澄
  • Organizer: 第36回日本神経科学大会
  • Place of Presentation: 京都市
  • Year and Date: 2013-06-23
• [Presentation] マーモセット脳と脊髄のインターネットアトラス (2013)
  • Author(s): 徳野博信
  • Organizer: 第2回日本マーモセット研究会 大会
  • Place of Presentation: 東京都
  • Year and Date: 2013-02-28
  • Invited
• [Presentation] マーモセット脳における神経伝達物質トランスポーター分布のデータベース化 (2012)
  • Author(s): 徳野博信, 田中いく子, 海津敬倫
  • Organizer: 第35回日本神経科学大会
  • Place of Presentation: 名古屋市
  • Year and Date: 2012-09-21
• [Book] 脳入門のその前に (2013)
  • Author(s): 徳野博信
  • Total Pages: 141
  • Publisher: 共立出版
• [Book] 脳 - 「かたち」と「はたらき」 (2012)
  • Author(s): Watson, Kirkcaldie, Paxinos 著 徳野博信訳
  • Total Pages: 211
  • Publisher: 共立出版
• [Book] The Marmoset Brain in Stereotaxic Coordinates (2011)
  • Author(s): George Paxinos, Charles Watson, Michael Petrides, Marcello Rosa, Hironobu Tokuno
  • Total Pages: 324
  • Publisher: Elsevier, San Diego
• [Remarks]
  • URL: http://marmoset-brain.org