2013 Fiscal Year Final Research Report
Noninvasive measurement of blood viscosity based on ultrasonic spectroscopy
| Project/Area Number |
23500563
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Medical systems
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| Research Institution | Tokyo Metropolitan University |
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Principal Investigator |
SATO Takayuki 首都大学東京, 理工学研究科, 助教 (90326017)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 赤血球凝集 / 血液粘性 / ピーク周波数 |
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| Research Abstract |
A novel technique of detecting the peak frequency of an ultrasonic reflection spectrum was proposed, with the aim of enhancing the sensitivity and accuracy of estimating the aggregation size of red blood cells (RBCs). Peak frequencies for stagnant and running suspensions prepared with monodisperse particles of graphite and acryl that were used to mimic aggregated RBCs were acquired. As a result, the relationships between particle diameter and peak frequency, which were independent of the material of the particles and flow rate, were obtained. For bidisperse samples, i.e., mixtures of two different sizes of particle samples, quantitative relationships corresponding to changes in the mixing ratio were observed. As a preparatory step for the experiments with real blood sample, a control method of sample particle aggregation was also established.
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Research Products
(7 results)
