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2013 Fiscal Year Final Research Report

Recovery and improvemant of muscle functions by bathing with artificially made high concentration CO2 water

Research Project

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Project/Area Number 23500623
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionTeikyo University of Science & Technology

Principal Investigator

HASHIMOTO MASAAKI  帝京科学大学, 医療科学部, 教授 (30156294)

Co-Investigator(Renkei-kenkyūsha) YAMAMOTO Noriyuki  日本赤十字北海道看護大学, 看護学部, 准教授 (70299329)
Project Period (FY) 2011 – 2013
Keywords人工炭酸泉 / 二酸化炭素の血管作用 / 皮膚血管拡張 / 筋血管拡張
Research Abstract

Skin blood vessel is dilated at the water temperature of around 35 degrees Celsius when we take a bath in carbon dioxide-rich (more than 1000ppm) hot-spring, and skin blood-flow increases. Animal experiments revealed that prostaglandin E2 (PGE2) is involved in this vasodilatation. In contrast, PGE1, PGI2 nor nitric oxide may not contribute to the vasodilation. Expression of enzymes contributing to the final step of the biosynthesis of those PGs was not changed during CO2-water bathing for 30 min. The results suggest that bathing with CO2-water may affect not the amount but the activity of the enzyme in the skin. On the other hand, the blood vessels in skeletal muscle of underwater body part was dilated, which produced increase of blood flow. Muscle soreness and hardness after resistance exercise was recovered by bathing with CO2-water more quickly than that with normal water. The result suggest that the CO2-water bath may improve a myofunction.

  • Research Products

    (26 results)

All 2014 2013 2012 2011

All Journal Article (12 results) Presentation (11 results) Book (3 results)

  • [Journal Article] Does Jin-Oh-Sui (mineral water) improve serum triglyceride levels? A pilot study2014

    • Author(s)
      Fujita, Y., Inoue, K., Amano, H., Uchida, T., Moriyama, S., Hashimoto, M
    • Journal Title

      Shimane J. Med. Sci

      Volume: 30 Pages: 87-93

  • [Journal Article] Candidate mechanism of skin vasodilation caused by contact with high concentration-CO2-water in the anesthetized rat2014

    • Author(s)
      Hashimoto, M. , Yamamoto, N
    • Journal Title

      J. Physiol. Sci

      Volume: 64 Pages: S217

  • [Journal Article] High concentration-CO2-water bath may reduce the muscle hardness and soreness after resistance exercise2014

    • Author(s)
      Yamamoto, N., Hashimoto, M
    • Journal Title

      J. Physiol. Sci

      Volume: 64 Pages: S264

  • [Journal Article] Molecular mechanism of a hamster brown adipose tissue enabling hibernation2013

    • Author(s)
      Hashimoto, M., Ohinata, H., Kitao, N
    • Journal Title

      J. Physiol. Sci

      Volume: 63 Pages: S266

  • [Journal Article] Medicine and Science in Sports and Exercise2013

    • Author(s)
      Yamamoto, N., Wada, T., Yanagi, H., Hashimoto, M
    • Volume
      45
    • Pages
      S154-S155
  • [Journal Article] 島根県奥出雲地方の鉱水長期投与によるマウスの血中脂質濃度と血糖値への影響2013

    • Author(s)
      平林菜つ美, 村木香保, 中村綾香, 深田英麿, 大日向浩, 橋本眞明
    • Journal Title

      日本生気象学会雑誌

      Volume: 50 Pages: S58

  • [Journal Article] 麻酔下ラットの人工二酸化炭素泉浸漬による骨格筋血流への効果2013

    • Author(s)
      村木香保, 平林菜つ美, 中村綾香, 深田英麿, 山本憲志, 橋本眞明
    • Journal Title

      日本生気象学会雑誌

      Volume: 50 Pages: S31

  • [Journal Article] Increased thermogenic capacity of brown adipose tissue under low temperature and its contribution to arousal from hibernation in Syrian hamsters2012

    • Author(s)
      Kitao, N., Hashimoto, M
    • Journal Title

      Am. J. Physiol

      Volume: 302 Pages: R118-R125

  • [Journal Article] Hibernation specific BAT activities in the golden hamster2012

    • Author(s)
      Hashimoto, M., Kitao, N
    • Journal Title

      J. Physiol. Sci

      Volume: 62 Pages: S52

  • [Journal Article] Bathingwith CO2-rich water improved physical flexibility in male college students2011

    • Author(s)
      Yamamoto, N. and Hashimoto, M
    • Journal Title

      J. Physiol. Sci

      Volume: 61 Pages: S240

  • [Journal Article] Brown adipose tissue thremogenesis in hibernating hamsters- hibaernation specific mechanism for Camp production during arousal from hibernation2011

    • Author(s)
      Kitao, N., Hashimoto, M
    • Journal Title

      J. Physiol. Sci

      Volume: 61 Pages: S245

  • [Journal Article] 運動後の人工炭酸泉浴がストレスを軽減させる可能性2011

    • Author(s)
      山本憲志, 根本昌宏, 橋本眞明
    • Journal Title

      日本生気象学会雑誌

      Volume: 48 Pages: S70

  • [Presentation] 麻酔下ラットの高濃度二酸化炭素水浸漬による皮膚血管拡張と媒介物質2014

    • Author(s)
      橋本眞明, 山本憲志
    • Organizer
      第91回日本生理学会大会
    • Place of Presentation
      鹿児島
    • Year and Date
      20140316-18
  • [Presentation] 人工炭酸泉浴がレジスタンス運動後の筋硬度と筋肉痛を低減させる可能性2014

    • Author(s)
      山本憲志, 橋本眞明
    • Organizer
      第91回日本生理学会大会
    • Place of Presentation
      鹿児島
    • Year and Date
      20140316-18
  • [Presentation] 島根県奥出雲地方の鉱水長期投与によるマウスの血中脂質濃度と血糖値への影響2013

    • Author(s)
      平林菜つ美, 村木香保, 中村綾香, 深田英麿, 大日向浩, 橋本眞明
    • Organizer
      第52回日本生気象学会大会
    • Place of Presentation
      米子
    • Year and Date
      20131101-02
  • [Presentation] 麻酔下ラットの人工二酸化炭素泉浸漬による骨格筋血流への効果2013

    • Author(s)
      村木香保, 平林菜つ美, 中村綾香, 深田英麿, 山本憲志, 橋本眞明
    • Organizer
      第52回日本生気象学会大会
    • Place of Presentation
      米子
    • Year and Date
      20131101-02
  • [Presentation] High-performance thermogenesis of brown adipose tissue under hypothermic condition during hibernation in Syrian hamsters2013

    • Author(s)
      Hashimoto, M., Ohinata, H., Kitao, N
    • Organizer
      37th congress IUPS
    • Place of Presentation
      Birmingham, UK
    • Year and Date
      20130721-26
  • [Presentation] Bathing with artificial high concentration CO2-water affected quiet standing posture control2013

    • Author(s)
      Yamamoto, N., Hashimoto, M
    • Organizer
      37th congress IUPS
    • Place of Presentation
      Birmingham, UK
    • Year and Date
      20130721-26
  • [Presentation] 冬眠を可能にするハムスター褐色脂肪組織の分子機構2013

    • Author(s)
      橋本眞明, 大日向浩, 北尾直也
    • Organizer
      第90回日本生理学大会
    • Place of Presentation
      東京
    • Year and Date
      20130327-29
  • [Presentation] ゴールデンハムスター褐色脂肪組織の冬眠相特異的な活性と冬眠行動におけるその重要性2012

    • Author(s)
      橋本眞明, 北尾直也
    • Organizer
      シンポジウム「新たにわかった褐色脂肪の生体機能とそのメカニズム」, 第89回日本生理学会大会
    • Year and Date
      20120029-31
  • [Presentation] Physiological evidence in spa-sure : cutaneous mediators of improved local blood circulation by CO2-hot spring water bathing2011

    • Author(s)
      Hashimoto, M., Yamamoto, N
    • Organizer
      19th International Congress of Biometeorology (ICB2011)
    • Place of Presentation
      Auckland, New Zealand
    • Year and Date
      20111205-08
  • [Presentation] Bathing with CO2-rich water improved physical flexibility and muscle stiffness in male college students2011

    • Author(s)
      Yamamoto, N., Hashimoto, M
    • Organizer
      19th International Congress of Biometeorology (ICB2011)
    • Place of Presentation
      Auckland, New Zealand
    • Year and Date
      20111205-08
  • [Presentation] 運動後の人工炭酸泉浴がストレスを軽減させる可能性2011

    • Author(s)
      山本憲志, 根本昌宏, 橋本眞明
    • Organizer
      第50回日本生気象学会大会
    • Place of Presentation
      京都
    • Year and Date
      20111104-05
  • [Book] Omega-6-eicosanoid may be involved in the cutaneous vasodilation mechanism of the rat bathing in CO2-rich water. F.Maraver & M.Z.Karagülle (Eds) 'Medical Hydrology and Balneology : Environmental Aspects'2012

    • Author(s)
      Hashimoto, M., Kitao, N., Yamamoto, N
    • Total Pages
      311-312
    • Publisher
      Publicaciones Universidad Complutense De Madrid
  • [Book] High concentration artificial CO2-water immersion facilitates a recovery from muscle fatigue after submaximal exercise. F.Maraver & M.Z.Karagülle (Eds) 'Medical Hydrology and Balneology : Environmental Aspects'2012

    • Author(s)
      Yamamoto, N., Hashimoto, M
    • Total Pages
      336-337
    • Publisher
      Publicaciones Universidad Complutense De Madrid
  • [Book] 13章自律神経系, 彼末・能勢編集「やさしい生理学改訂第6版」2011

    • Author(s)
      橋本眞明
    • Total Pages
      233-244
    • Publisher
      朝倉書店

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Published: 2015-07-16  

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