2013 Fiscal Year Final Research Report
Effect of exercise training on endogenous carbon monoxide exhalation in humans.
| Project/Area Number |
23500779
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Sports science
|
|---|
| Research Institution | Toyohashi University of Technology |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
SAITO Yoshihiro 豊橋技術科学大学, 大学院・工学研究科, 准教授 (00303701)
SAKUMA Kunihiro 豊橋技術科学大学, 工学部, 准教授 (60291176)
NIWAYAMA Masatsugu 静岡大学, 工学部, 准教授 (40334958)
|
|---|
| Project Period (FY) |
2011 – 2013
|
| Keywords | ガス状伝達物質 / 一酸化炭素 / 硫化水素 / ヘムオキシゲナーゼ / パルスオキシメータ / カーボライザー |
|---|
| Research Abstract |
In the present study we aimed to measure exhaled carbon monoxide (CO) during and after exercise in smokers and non-smokers. We could observe that exhaled carbon oxide increased relatve to exercise intensity and decreased rapidly after exercise. The amounts of CO exhalation in smokers were significantly larger than those of non-smokers. We also attempted to develop a prototype model to estimate carboxyhemoglobin concentrations (COHb) transcutaneously in the blood using multi-wavelength optical sources. The COHb could be continuously measured by a prototype model, however problems relevant to the stability and resolution still remained. Furthermore, we also measured the expression of heme oxygenase-1 and -2 which are the enzymes producing CO in mice, and found that the expression of these enzymes in the skeletal muscles increased with acute exercise and strength training.
|
