2013 Fiscal Year Final Research Report
Genetic strain differences for strength training trainablitiy in rats and its application for understanding of muscle hypertrophy
| Project/Area Number |
23500788
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Sports science
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| Research Institution | Nippon Sport Science University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
OCHI Eisuke 明治学院大学, 教養部, 准教授 (90468778)
HIROSE Tatsuro 横浜桐蔭大学, スポーツ健康科学部, 講師 (80468800)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 筋肥大 / 動物モデル / ラット / 個体差 / タンパク質合成 / タンパク質分解 |
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| Research Abstract |
It has been well recognized that trainability for strength training varies depending on individual difference. In this study, we originally developed strength training model for rats and found that genetic strain difference exist for strength training. Sprague Dawley rat shows significant muscle hypertrophy with strength training but Wistar rats did not. We also found that mixture of different muscle contraction modes (isometric contractions and isometric contractions) and low frequency electrical stimulation are effective for muscle hypertrophy in Wistar strain with low response for strength training. Since electrical stimulation has been used in rehabilitation, low frequency electrical stimulation will be useful not only for low responder but for injured athletes.
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