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2013 Fiscal Year Final Research Report

Study on nutritional property and diabetes prevention effects of Silkworm pupae (Bombyx mori)

Research Project

  • PDF
Project/Area Number 23500947
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Eating habits, studies on eating habits
Research InstitutionIida Women's Junior College

Principal Investigator

TOMOTAKE Hiroyuki  飯田女子短期大学, その他部局等, 教授 (90300136)

Project Period (FY) 2011 – 2013
Keywords蚕サナギ / 糖質分解酵素阻害作用 / 血糖上昇抑制作用
Research Abstract

This study was performed to evaluate the nutritional value and bioactive component of silkworm pupase (Bombyx mori) and the alfa-glucosidase inhibitory effect of water extracts of that. Hot water extract of silkworm pupase inhibited angiotensin-converting enzyme, porcin panreatic alfa-glucosidase and an increase of blood glucose level in rats. Phosphate buffer extract of silkworm pupase has DPPH radical scavenging activity. Methanol extract of silkworm pupase has antibacterial activity against Staphylococcus aureus. These results suggest that silkworm pupase is a new source of bioactive components and alfa-glucosidase inhibitor.

  • Research Products

    (15 results)

All 2014 2013 2012 2011

All Journal Article (6 results) Presentation (9 results)

  • [Journal Article] Treatment with buckwheat bran extract prevents the elevation of serum triglyceride levels and fatty liver and in KK-Ay mice2014

    • Author(s)
      Hosaka T, Sasaga S, Yamasaka Y, Nii Y, Edazawa K, Tsutsumi R, Shuto E, Okahisa N, Iwata S, Tomotake T, Sakai T
    • Journal Title

      J Med Inves

      Volume: 61(印刷中) Pages: 3-4

  • [Journal Article] Burdock fermented by Aspergillus awamori elevates cecal Bifidobacterium, and reduces fecal deoxycholic acid and adipose tissue weight in rats fed a high-fat diet2013

    • Author(s)
      Okazaki Y, Sitanggang NV, Sato S, Ohnishi N, Inoue J, Iguchi T, Watanabe T, Tomotake H, Harada K, Kato N
    • Journal Title

      Biosci Biotechnol Biochem

      Volume: 77(1) Pages: 53-7

  • [Journal Article] An autoclave treatment reduces the solubility and antigenicity of an allergenic protein found in buckwheat flour2012

    • Author(s)
      Tomotake H, Yamazaki R, Yamato M
    • Journal Title

      J Food Prot

      Volume: 75(6) Pages: 1172-5

    • DOI

      10.4315/0362-028X.JFP-11-368

  • [Journal Article] Consumption of vitamin B_6 reduces fecal ratio of lithocholic acid to deoxycholic acid, a risk factor for colon cancer, in rats fed a high-fat diet2012

    • Author(s)
      Okazaki Y, Utama Z, Suidasari S, Zhang P, Yanaka N, Tomotake H, Sakaguchi E, Kato N
    • Journal Title

      J Nutr Sci Vitaminol (Tokyo)

      Volume: 58(5) Pages: 366-70

  • [Journal Article] Consumption of a resistant protein, sericin, elevates fecal immunoglobulin A, mucins, and cecal organic acids in rats fed a high-fat diet2011

    • Author(s)
      Okazaki Y, Tomotake H, Tsujimoto K, Sasaki M, Kato N
    • Journal Title

      J Nutr

      Volume: 141(11) Pages: 1975-81

    • DOI

      10.3945/jn.111.144246

  • [Journal Article] Extracts of common buckwheat bran prevent sucrose digestion2011

    • Author(s)
      Hosaka T, Nii Y, Tomotake H, Ito T, Tamanaha A, Yamasaka Y, Sasaga S, Edazawa K, Tsutsumi R, Shuto E, Okahisa N, Iwata S, Sakai T
    • Journal Title

      J Nutr Sci Vitaminol (Tokyo)

      Volume: 57(6) Pages: 441-5

  • [Presentation] 蚕サナギの 1-デオキシノジリマイシン含量および糖質分解酵素阻害作用2014

    • Author(s)
      友竹浩之, 片桐充昭
    • Organizer
      日本農芸化学会学術総会 2013年度大会
    • Place of Presentation
      明治大学
    • Year and Date
      2014-03-29
  • [Presentation] ヤーコン粉末の特徴と利用2013

    • Author(s)
      友竹浩之, 千裕美
    • Organizer
      第60回日本栄養改善学会学術総会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2013-09-14
  • [Presentation] 小麦アレルギー対応に向けた米粉およびホワイトソルガム粉の利用2013

    • Author(s)
      友竹浩之, 柴田あずさ, 長谷部遥, 花井希, 望月希代, 柴本むつ美
    • Organizer
      第67回日本栄養食糧学会
    • Place of Presentation
      名古屋大学
    • Year and Date
      2013-05-26
  • [Presentation] 蚕サナギおよびイナゴタンパク質の栄養特性2013

    • Author(s)
      友竹浩之, 片桐充昭, 柴本むつ美
    • Organizer
      日本農芸化学会学術総会 2013年度大会
    • Place of Presentation
      東北大学
    • Year and Date
      2013-03-27
  • [Presentation] 高圧加熱処理がそばタンパク質の溶解性と抗原性に及ぼす影響2012

    • Author(s)
      友竹浩之, 柴本むつ美, 富口由紀子
    • Organizer
      第59回日本栄養改善学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2012-09-13
  • [Presentation] キクイモ粉末の特徴と利用2012

    • Author(s)
      友竹浩之, 牛山瑞穂, 園原一吉
    • Organizer
      第66回日本栄養食糧学会
    • Place of Presentation
      東北大学
    • Year and Date
      2012-05-20
  • [Presentation] 高蛋白質そば粉抽出物の血糖上昇抑制作用2012

    • Author(s)
      友竹 浩之, 柴本 むつ美, 新居 佳孝
    • Organizer
      日本農芸化学会学術総会 2012年度大会
    • Place of Presentation
      京都女子大学
    • Year and Date
      2012-03-25
  • [Presentation] 黒ソバ粉が肥満・糖尿病マウスの血糖上昇に及ぼす影響2011

    • Author(s)
      友竹浩之, 柴本むつ美, 富口由紀子
    • Organizer
      第58回日本栄養改善学会学術総会
    • Place of Presentation
      広島国際会議場
    • Year and Date
      2011-09-09
  • [Presentation] ポリフェノール摂取は高脂肪食摂取ラットの糞中ステロール組成を改善する2011

    • Author(s)
      友竹浩之, Yunkyung Han, 原口智, 松本やよい, Yonghui Xu, 岡崎由佳子, 峰尾茂, 森山明穂, 井上淳詞, 加藤範久
    • Organizer
      第65回日本栄養食糧学会
    • Place of Presentation
      お茶の水女子大学
    • Year and Date
      2011-05-15

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Published: 2015-07-16  

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