Role of dietary fiber in the body-Prevention from the lifestyle related disease-

2013 Fiscal Year Final Research Report

• Project/Area Number: 23500951
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Eating habits, studies on eating habits
• Research Institution: Tokyo Gakugei University
• Principal Investigator: MINAMI Michiko 東京学芸大学, 教育学部, 教授 (70272432)
• Co-Investigator(Renkei-kenkyūsha): KAMEI Asuka 神奈川科学アカデミー, アンチエイジングプロジェクト, 研究員 (40514112) ; SHINOZAKI Fumika 神奈川科学アカデミー, アンチエイジングプロジェクト, 研究員 (00359647)
• Project Period (FY): 2011 – 2013
• Keywords: 食物繊維 / 腸内細菌叢 / DNAマイクロアレイ / ラット

Research Abstract

In 40-week-old male wister rats reared for one week with food containing 10%, 5%, and 2% cellulose as dietary fiber, suppression of lipid synthesis system was seen in the gene expression of the liver. Although , in regard to lipid levels in liver, the total cholesterol level was seen to significantly increase by increasing the intake of cellulose. Also, a significant variation in the intestinal flora due to the variation of dietary fiber intake was detected. The observation of the change in gastrointestinal gene expression due to the amount of cellulose intake is the report which shows that cellulose that is not absorbed into the body has a function to indirectly control the gene expression in the body.

Research Products

• [Journal Article] Construction of a crown ether-like supramolecular library by conjugation of genetically-encode peptide linkers displayed on bacteriophage T7 (2014)
  • Author(s): Keisuke Fukunaga, Takaaki Hatanaka, Yuji Ito, Michiko Minami and Masumi Taki
  • Journal Title: Chemical communication Volume: 50 (30) Pages: 3887-4012
  • DOI: 10.1039/c4cc00811a
  • Peer Reviewed
• [Journal Article] Effects of inhaled(S)-linalool on hypothalamic gene expression in rats under restraint stress (2013)
  • Author(s): Yamamoto N., Fujiwara S., Saito-Iisumi K., Kamei A., Shinozaki F., Watanabe Y., Abe K. and Nakamura A
  • Journal Title: Biosci. Biotechnol. Biochem Volume: 77(12) Pages: 2013-8
  • DOI: 10.1271/bbb.130524
  • Peer Reviewed
• [Journal Article] Influence of a short-term iron-deficient diet on hepatic gene expression on profiles in rats (2013)
  • Author(s): Kamei A. Watanabe Y, Kondo K, Okada S, Shinozaki F, Ishijima Y, Nakai Y, Kondo T, Arai S, and Abe K
  • Journal Title: PloS One Volume: 8(6) Pages: e65732
  • DOI: 10.1371/journalpone.0065732
  • Peer Reviewed
• [Presentation] セルロース及びセルロース誘導体添加パンの品質 (2013)
  • Author(s): 西原百合枝, 南道子, 新垣有紀, 川原志織, 柴田有理, 江藤和佳子, 朝倉富子, 舟木淳子
  • Organizer: 日本調理科学会平成25年度年度大会
  • Place of Presentation: 奈良市 奈良女子大学
  • Year and Date: 2013-08-24
• [Presentation] 喉越しを数値化する~オトガイ下筋の筋電位に及ぼすゼリー状オブラートの効果~ (2013)
  • Author(s): 福居篤子, 南道子, 朝倉富子
  • Organizer: 第28回日本薬剤学会
  • Place of Presentation: 名古屋 ウィンクあいち
  • Year and Date: 2013-05-23
• [Presentation] 製パンへのセルロース及びセルロース誘導体添加の影響 (2013)
  • Author(s): 西原百合枝, 南道子, 江藤和佳子, 朝倉富子, 舟木淳子
  • Organizer: 第65回日本家政学会
  • Place of Presentation: 東京 昭和女子大
  • Year and Date: 2013-05-18
• [Book] 調理学 - 生活の基盤を考える (2013)
  • Author(s): 吉田 勉 監修, 南 道子, 舟木 淳子編著 高崎 禎子, 柘植 光代, 宅間 真佐代, 松藤 泰代, 平 和香子, 三宅 紀子, 畦 五月
  • Total Pages: 192, 1-2, 58-73, 182-187
  • Publisher: 学文社
• [Book] 看護学大事典 (2012)
  • Author(s): 南 道子, 他279 名
  • Total Pages: 2453, 393, 742, 1602, 1557
  • Publisher: メディカルフレンド社