2014 Fiscal Year Final Research Report
Study on the oxazolone-oxazolone cluster damage
| Project/Area Number |
23510069
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Risk sciences of radiation/Chemicals
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| Research Institution | Tokushima Bunri University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
OYOSHI Takanori 静岡大学, 理学部, 講師 (80406529)
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| Project Period (FY) |
2011-04-28 – 2015-03-31
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| Keywords | 酸化 / クラスター損傷 / DNAポリメラーゼ |
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| Outline of Final Research Achievements |
In this research, the 6mer oligomer containing Oz was ligated with 13mer and 11mer oligomers and the complimentary 30mer oligomer, and then the 30mer oligomer containing OzOz was prepared. Using DNA polymerase alpha, beta, zeta, eta, kappa, Klenow fragment or REV1, primer elongation was performed.
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| Free Research Field |
生物有機化学
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