2014 Fiscal Year Final Research Report
Pathophysiological Mechanisms of Microvascular Angina and Feeling of Cold and Effect of Kampo Medicine in Women
| Project/Area Number |
23510349
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Gender
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| Research Institution | Oita University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
MIYAZAKI Hiroko 大分大学, 医学部, 医員 (20555205)
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| Project Period (FY) |
2011-04-28 – 2015-03-31
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| Keywords | 冷え症 / 血管内皮機能 / 自律神経機能 / 血管弾性 / 心拍変動 / 漢方薬 |
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| Outline of Final Research Achievements |
We investigated the relationship between feeling of cold, vascular endothelial function and autonomic nervous function in young healthy women. Reactive hyperemia index (RHI), parameter of vascular endothelial function, was not significantly different between women with and without coldness, but augmentation index (AI) which is the parameter of aortic stiffness, and parasympathetic tone calculated by heart rate variability tended to attenuate in women with coldness. After oral administration of Japanese traditional Kampo medicine for 14 days, the peripheral skin temperature significantly increased in women with coldness. However, RHI, AI and autonomic tone did not significantly changed after Kampo treatment in women with coldness.
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| Free Research Field |
循環器内科学
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