2013 Fiscal Year Final Research Report
Development of methodology to quantify electron transfer between single molecules
| Project/Area Number |
23550103
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Analytical chemistry
|
|---|
| Research Institution | Osaka Prefecture University |
|---|
Principal Investigator |
NISHINO Tomoaki 大阪府立大学, 工学(系)研究科(研究院), 准教授 (80372415)
|
|---|
| Project Period (FY) |
2011 – 2013
|
| Keywords | 走査型トンネル顕微鏡 / 分子探針 / 相互作用 / 電子移動 / 分子エレクトロニクス / DNA / バイオセンサ |
|---|
| Research Abstract |
In the present research project, we developed the first methodology by using molecular tip of scanning tunneling microscopy to quantify electron transfer taking place between a single molecule and adjacent another single molecule. This methodology allowed us to, for example, reveal that a hydrogen bond conducts electrons better than a covalent bond at short range. Moreover, we systematically investigated the electron transfer between single molecules mediated by a variety of chemical interactions. These studies provided novel insights and phenomena mandatory for the future realization of molecular electronics.
In addition, we demonstrated that single-molecule detection of DNA can be achieved based on the methodology for the measurement of the electron transfer between single molecules. Single-stranded DNA was utilized as a probe tip, and hybridization of this DNA tip and target DNA induce electron tunneling through the resulting DNA duplex.
|
