2013 Fiscal Year Final Research Report
Development of Matal Complex Sensor Possessing a Neurotransmitter-Responce on Near-Infrared Spectroscopy
| Project/Area Number |
23550104
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Analytical chemistry
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| Research Institution | Sophia University |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2013
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| Keywords | 糖認識 / 化学センサー / 近赤外吸収 / ルテニウム錯体 / 吸収スペクトル / シクロデキストリン / 超分子複合体 / ドーパミン |
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| Research Abstract |
The purpose of this study is to develop a neurotransmitter response on near-infrared spectroscopy using (.beta.-diketonato) ruthenium complexes. To realize this objective, a naphthylboronic acid-coordinated (.beta.-diketonato)ruthenium complex has been designed and synthesized. This metal complex was evaluated with electrochemistry and electronic spectra. The results revealed that this complex exhibited a near-infrared absorption band and a sugar recognition function in 80% water – 20% acetonitrile solution. Moreover, the dopamine recognition function of the supramolecular chromogenic probe/cyclodextrin complex was evaluated from their UV-Vis or fluorescence spectra in aqueous solution.
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