2013 Fiscal Year Final Research Report
Development and application of stable spin-label reagent for in vivo analysis
Project/Area Number |
23550187
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Chemistry related to living body
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Research Institution | Yamagata University |
Principal Investigator |
HATANO Bunpei 山形大学, 理工学研究科, 准教授 (20333990)
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Co-Investigator(Renkei-kenkyūsha) |
OGATA Tateaki 山形大学, 大学院理工学研究科, 名誉教授 (50091830)
KIJIMA Tatsuro 山形大学, 大学院理工学研究科, 准教授 (50272084)
ITO Tomohiro 山形大学, 大学院理工学研究科, 准教授 (60361276)
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Project Period (FY) |
2011 – 2013
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Keywords | スピンラベル剤 / 農薬ミュータント / ESR |
Research Abstract |
We developed new spin-label reagents based of isoindole framework bearing bulky alkyl groups near nitroxyl radical. The spin labels showed strong resistance against the reduction with L-sodium ascorbate. We also developed the synthesis method of agricultural chemicals bearing spin-labels using click reaction.
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Research Products
(14 results)
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[Journal Article] Enantioresolution of 2,2'-bis(diphenylphosphino)-1,1'-bi naphthyl oxide using inclusion com- plex with chiral 2,2'-di- hydroxy-1,1'-binaphtyl2011
Author(s)
B. Hatano, K. Hashimoto, H. Katagiri, T, Kijima, S. Murakami, S. Matsuba, M. Kusakari
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Journal Title
J. Org. Chem.
Volume: 77
Pages: 3595–3597
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