2013 Fiscal Year Final Research Report
Biomimetic fabrication of chitosan/calcium carbonate core-shell type composite microparticles
| Project/Area Number |
23550231
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Inorganic industrial materials
|
|---|
| Research Institution | The University of Shiga Prefecture |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2011 – 2013
|
| Keywords | ハイブリッド材料 / キトサン / バイオミネラリゼーション / ドラッグデリバリーシステム / 微粒子 / コアシェル / ソフトケミカルプロセス |
|---|
| Research Abstract |
Chitosan microparticle having calcium carbonate shell was fabricated through a biomimetic process. A hydrophilic fluorescein derivative "uranine" was introduced into the chitosan core particle before the shell formation. The uranine release behavior from the core-shell particles was observed at various pH conditions. The results suggested that the calcium carbonate shell had controlled uranine release from chitosan core particle.
|
