2013 Fiscal Year Final Research Report
Regulation of homeostasis by absorption and excretion in the digestive tract
| Project/Area Number |
23570006
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Genetics/Genome dynamics
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| Research Institution | Okayama University |
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Principal Investigator |
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| Research Collaborator |
KIFUKU Naoto 岡山大学, 大学院自然科学研究科, 大学院生
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| Project Period (FY) |
2011 – 2013
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| Keywords | ショウジョウバエ / マルピーギ管 / ストレス応答 |
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| Research Abstract |
Malpighian tubules of Drosophila melanogaster have functions homologous to those of mammalian kidney, and maintain homeostasis by excreting waste matter from the body fluid. This study has shown that the homeodomain transcription factor Defective proventriculus (Dve) is essential for functional differentiation of these cells and their stress response to high-salt diet.
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[Journal Article] Pranidhi Sood, Nina Vogt, Rudy Behnia, Daniel Vasiliauskas, Elizabeth McDonald, Baotong Xie, Sebastian Koenig, Reinhard Wolf, Tiffany Cook, Brian Gebelein, Edo Kussell, Hideki Nakagoshi* and Claude Desplan* (* corresponding authors) Interlocked feedforward loops control cell-type-specic Rhodopsin expression in the Drosophila eye2011
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