2013 Fiscal Year Final Research Report
Study on anteroposterior and dorsoventral axes in echinoderm
| Project/Area Number |
23570248
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Developmental biology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
AKASAKA Koji 東京大学, 理学(系)研究科(研究院), 教授 (60150968)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 棘皮動物 / 体軸 / Hox / 神経系 |
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| Research Abstract |
Pentameral symmetry is a characteristic of echinoderms, which do not have a clear anterior-posterior axis and lack head structures. Hox cluster genes are broadly conserved across deuterostomes and protostomes, and are demonstrated a linear cluster structure in the genome. Expression patterns on the anterior-posterior axis are also identical in the ordering of the genes in the genome and in developmental stages, demonstrating a relation to formation patterns along the anterior posterior axis. The spatial expression patterns of crinoid Oxycomanthus japonicus and sea cucumber Apostichopus japonicus were examined. Co-linearity expression of the Hox gene cluster along the axis is not observed in Oxycomanthus japonicus; however the co-linearity expression along the gut in Apostichopus japonicus; which has obvious external anterior posterior axis, is observed. The results imply that the function of Hox cluster genes is different in different groups of echinoderm.
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Research Products
(21 results)
