2013 Fiscal Year Final Research Report
The important roles of intestinal cells in responses to dietary fibers
| Project/Area Number |
23580163
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Food science
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| Research Institution | Gifu University |
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Principal Investigator |
YABE Tomio 岐阜大学, 応用生物科学部, 准教授 (70356260)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 食物繊維 / ペクチン / フィブロネクチン / Caco-2細胞 / ヘパラン硫酸 / インテグリン |
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| Research Abstract |
We found that intestinal epithelial cells recognized a pectic polysaccharide through the fibronectin located around tight junctions and altered sulfated structure of heparan sulfate on the cell surface through integrin. These findings show that functions of dietary fiber are not only exerted by physicochemical properties or enterobacteria.
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Research Products
(10 results)
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[Journal Article] The simple refinement method of arabinan polysaccharides by the alcohol extraction from prune, Prunus domestica L2013
Author(s)
Hara, Y., Mizukawa, H., Yamamoto, H., Ikami, T., Kato, K., and Yabe, T.
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Journal Title
Biosci. Biotechnol. Biochem
Volume: 77
Pages: 2137-2139
DOI
Peer Reviewed
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[Presentation] A specific structure in the pectin from prune recognizes fibronectin and affects on the expression level of polyamines in Caco-2 cells2013
Author(s)
Yabe, T., Itoh, C., Honda, A., Ishikawa, M., Nakamura, A., Yamamoto, H., Ikami, T., and Kanamaru, Y.
Organizer
EPNOE 2013 International Polysaccharides Conference
Place of Presentation
Nice, France
Year and Date
2013-10-24
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