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2013 Fiscal Year Final Research Report

The development of a method for determining rapidly the abuse of gateway drugs, such as slimming drugs and cannabis

Research Project

  • PDF
Project/Area Number 23590055
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Physical pharmacy
Research InstitutionHoshi University

Principal Investigator

SAITO KOICHI  星薬科大学, 薬学部, 教授 (40386347)

Project Period (FY) 2011 – 2013
Keywords法科学 / 大麻 / 脱法ハーブ / 痩身薬 / ゲートウェイドラッグ / スクリーニング / 分析法
Research Abstract

A chiral analytical method of alfa-lipoic acid, a kind of slimming drugs, was constructed using LC-TOFMS. The method made it possible to determine the display violations of dietary preparations and supplements for slimming purposes.
A rapid screening method of synthetic cannabinoids and cathinones in illegal herbal products was constructed by using DART-TOF-MS. This method was also able to discriminate between synthetic cannabinoids and cannabis plant.
30 kinds of analgesics and adjuvant analgesics were selected as medical drugs, capable of causing abuse, and the analytical method of the drugs was constructed by using LC/TOF-MS.

  • Research Products

    (12 results)

All 2013 2012 2011 Other

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (6 results) Remarks (1 results) Patent(Industrial Property Rights) (2 results) (of which Overseas: 2 results)

  • [Journal Article] クロマトグラフィー/質量分析法による健康食品中のα-リポ酸の光学異性体の定量分析2012

    • Author(s)
      小林由幸、斉藤貢一、岩崎雄介、伊藤里恵
    • Journal Title

      分析化学

      Volume: 61(2) Pages: 109-114

    • Peer Reviewed
  • [Journal Article] リアルタイム直接分析(DART)-TOF-MSを用いる合成カンナビノイド系及び合成カチノン系薬物の迅速スクリーニング法2012

    • Author(s)
      樋口美代子、斉藤貢一
    • Journal Title

      分析化学

      Volume: 61(8) Pages: 705-711

    • Peer Reviewed
  • [Journal Article] Analysis of drugs of abuse in biological specimens2011

    • Author(s)
      K. Saito、R. Saito、Y. Kikuchi、Y. Iwasaki、R. Ito
    • Journal Title

      J. Health Sci

      Volume: 57(6) Pages: 472-487

    • Peer Reviewed
  • [Presentation] 固相分散抽出―LC/TOF-MS法によるヒト血清中鎮痛薬・鎮痛補助薬(計30種)の一斉分析2013

    • Author(s)
      西山莉可、岩崎雄介、伊藤里恵、斉藤貢一
    • Organizer
      第57回日本薬学会関東支部大会
    • Place of Presentation
      東京都(帝京大学板橋キャンパス)
    • Year and Date
      2013-10-26
  • [Presentation] 健康食品中α-リポ酸の光学異性化の検討2012

    • Author(s)
      小林由幸、斉藤貢一、岩崎雄介、伊藤里恵
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道
    • Year and Date
      20120328-31
  • [Presentation] 固相分散抽出-LC/TOF-MS法によるヒト血清および尿中バルビツール酸系薬物の分析2012

    • Author(s)
      小鍛治好恵、斉藤貢一、菊池優、岩崎雄介、伊藤里恵
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道
    • Year and Date
      20120328-31
  • [Presentation] 固相分散抽出-LC/MS法による血清中バンコマイシンの分析2012

    • Author(s)
      坂本泰洋、斉藤貢一、篠塚郁美、神野佑輝、岩崎雄介、伊藤里恵
    • Organizer
      第56回日本薬学会関東支部大会
    • Place of Presentation
      東京都
    • Year and Date
      2012-10-13
  • [Presentation] 改良型固相分散抽出-LC/TOF-MS法による生体試料中のバルビツール酸系薬物の分析2011

    • Author(s)
      斉藤貢一、小鍛冶好恵、菊地優、小林由幸、岩崎雄介、伊藤里恵
    • Organizer
      日本法科学技術学会第17回学術集会
    • Place of Presentation
      東京都
    • Year and Date
      2011-11-17
  • [Presentation] LC/MS/MSを用いた尿中α-リポ酸の光学異性体分析2011

    • Author(s)
      小林由幸、斉藤貢一、岩崎雄介、伊藤里恵
    • Organizer
      第55回日本薬学会関東支部大会
    • Place of Presentation
      千葉県
    • Year and Date
      2011-10-08
  • [Remarks]

    • URL

      http://www.hoshi.ac.jp/home/kyoiku/kyoushitsuhgaid/2kyoushitsu.bunseki.html

  • [Patent(Industrial Property Rights)] 遠心分離用チューブ2011

    • Inventor(s)
      斉藤貢一
    • Industrial Property Rights Holder
      星薬科大学
    • Industrial Property Rights Type
      実用新案
    • Industrial Property Number
      実願2011-005642号
    • Filing Date
      2011-09-27
    • Overseas
  • [Patent(Industrial Property Rights)] 遠心分離用チューブ2011

    • Inventor(s)
      斉藤貢一
    • Industrial Property Rights Holder
      星薬科大学
    • Industrial Property Rights Type
      実用新案
    • Industrial Property Number
      3172219
    • Acquisition Date
      2011-11-16
    • Overseas

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Published: 2015-07-16  

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