2013 Fiscal Year Final Research Report
Sequence-based typing of Legionella pneumophila isolates in Japan
| Project/Area Number |
23590530
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Bacteriology (including Mycology)
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| Research Institution | National Institute of Infectious Diseases |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2013
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| Keywords | レジオネラ / Legionella pneumophila / sequence-based typing / 遺伝子型別 / 浴槽水 / 冷却塔水 / 土壌 |
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| Research Abstract |
Legionella pneumophila (Lp), the causative agent of Legionnaires' disease, grows in the bath water. Over half of Legionella pneumonia patients, however, do not use the bathing facility, and in most such cases, the sources of infection are not clear. I examined the genotypes of Lp strains derived from various environments: cooling tower water, soil, fountains, and shower water as well as bath water, in order to compare the genotypes of Lp strains derived from patients. The genotypes of Lp strains derived from patients who were suspected to infect Lp through bath water were belonged to the genotype groups including most Lp strains derived from bath water. The genotypes of Lp strains derived from patients whose sources of infection were unknown were belonged to the genotype groups including Lp strains derived from environments other than bath water. Therefore inspection and hygiene management of various environments other than bathing facilities as the source of infection are important.
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Research Products
(10 results)
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[Journal Article] A case of pneumonia caused by Legionella pneumophila serogroup 12 and treated successfully with imipenem2014
Author(s)
Nishizuka M, Suzuki H, Ara T, Watanabe M, Morita M, Sato C, Tsuchida F, Seto J, Amemura-Maekawa J, Kura F, Takeda H
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Journal Title
J Infect Chemother
Volume: 20
Pages: 390-3
Peer Reviewed
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[Journal Article] Working Group for Legionella in Japan. Distribution of monoclonal antibody subgroups and sequence-based types among Legionella pneumophila serogroup 1 isolates derived from cooling tower water, bathwater, and soil in Japan2012
Author(s)
Amemura-Maekawa J, Kikukawa K, Helbig JH, Kaneko S, Suzuki-Hashimoto A, Furuhata K, Chang B, Murai M, Ichinose M, Ohnishi M, Kura F
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Journal Title
Appl Environ Microbiol
Volume: 12
Pages: 4263-70
Peer Reviewed
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[Presentation] Grouping of clinical isolates of Legionella pneumophila SG1 in Japan, using SBT analysis and environmental habitats2012
Author(s)
Junko Amemura-Maekawa, Fumiaki Kura, Hiroyuki Tawara, Yuko Watanabe, Junko Isobe, Shinobu Tanaka, Hiroshi Nakajima Shuji Yoshino, Shinjiro Abe, Takako Misaki, Tomoe Shimada, Taku Wakui, Yuki Tada, Makoto Ohnishi
Organizer
ESGLI 2012 (1st Meeting of the ESCMID Study Group for Legionella Infections)
Place of Presentation
Dresden, Germany
Year and Date
20120900
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