Epidemiologic study on the origin of lifestyle-related disease: the combined effect of intrauterine environment and lifestyle after birth.

2014 Fiscal Year Final Research Report

• Project/Area Number: 23590787
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Public health/Health science
• Research Institution: Nagoya University
• Principal Investigator: TAMAKOSHI Koji 名古屋大学, 医学(系)研究科(研究院), 教授 (30262900)
• Co-Investigator(Renkei-kenkyūsha): YATSUYA Hiroshi 藤田保健衛生大学, 医学部, 教授 (30324437)
• Project Period (FY): 2011-04-28 – 2015-03-31
• Keywords: 生活習慣病 / 糖尿病 / 出生時体重 / 喫煙

Outline of Final Research Achievements

We conducted the epidemiologic study to elucidate the combined effect of intrauterine environment and lifestyle after birth on the development of lifestyle-related disease. Birth weight was used as an index of intrauterine environment. In this study, the combined effect of birth weight and smoking behavior on the development of type 2 diabetes was examined. The subjects born with less than 2500g had a significant high risk of type 2 diabetes independent of smoking behavior after birth. The subjects with smoking history had a higher risk of type 2 diabetes than those with no smoking history in each birth weight group. Interestingly the subjects who were born with 3500g and over and had smoking history presented a similar high risk of type 2 diabetes to those born with less than 2500g.

Free Research Field

公衆衛生学