2013 Fiscal Year Final Research Report
Prospective study of association between high plasma fetuin-A levels and incident ischemic stroke
| Project/Area Number |
23590828
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Kurume University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
HIRAI Yuji 久留米大学, 医学部, 講師 (70309780)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 疫学 / フェチュインA / 脳卒中 / メタボリック症候群 / 地域住民 |
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| Research Abstract |
Whatever the mechanisms are, elevations of fetuin-A were associated with metabolic syndrome and hypercholesterolemia, which are strong risk factors for cerebro-cardiovascular diseases. In fact, many clinical studies reported a high incidence of cerebro-cardiovascular diseases in subjects with high fetuin-A levels.
We prospectively investigated that higher fetuin-A levels are related to incident ischemic stroke in our cohort, and we also elucidated the significance of plasma fetuin-A as a risk factor of the stroke in a general Japanese cohort.
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