2013 Fiscal Year Final Research Report
The effects of osteoporosis on the development of atherosclerotic disease in the elderly
| Project/Area Number |
23590833
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Public health/Health science
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| Research Institution | Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology |
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Principal Investigator |
YOSHIDA Hideyo 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究部長 (00242735)
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| Co-Investigator(Renkei-kenkyūsha) |
SHIMIZU Yoko 東京都健康長寿医療センター研究所, 研究員 (90415505)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 骨粗鬆症 / 動脈硬化 / 脳卒中 / 心筋梗塞 |
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| Research Abstract |
With aging, calcium absorbed from the bone can be easily deposited in the arteries, causing arteriosclerosis. Therefore, we investigated strokes and myocardial infarctions among elderly people who participated in the osteoporosis screening examination. There were a total of 338 participants from the Akita prefecture, and 891 people from Tokyo. As a result, the odds ratio (OR) (and 95% confidence interval) of bone mass (low-to-high value) for new strokes was 1.22 (0.97-1.49) in men, and 1.18 (0.29-2.05) in women. Furthermore, the OR for new ischemic disease was 1.44 (0.63-2.26) in men, and 1.15 (-0.26-2.56) in women. Therefore, there seems to be a greater risk of stroke in men with low bone mass.
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