Epidemiological studies on the significance of the measurement of aortic calcification and aortic diameter as a cardiovascular risk factor

2013 Fiscal Year Final Research Report

• Project/Area Number: 23590837
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Public health/Health science
• Research Institution: Osaka Medical Center for Health Science and Promotion
• Principal Investigator: OKADA TAKEO 公益財団法人大阪府保健医療財団大阪がん循環器病予防センター(予防推進部・循環器病, その他部局等, その他 (70450921)
• Co-Investigator(Kenkyū-buntansha): OHIRA Tetsuya 福島県立医科大学, 医学部疫学講座, 主任教授 (50448031) ; KITAMURA Akihiko 大阪がん循環器病予防センター (80450922)
• Project Period (FY): 2011 – 2013
• Keywords: 大動脈石灰化 / 頸動脈内膜肥厚 / 冠動脈石灰化 / 循環器疾患危険因子

Research Abstract

We tried to quantify the measurement of aortic calcification and pericardial fat on the basis of the CT image. Quantification of pericardial fat could be carried out smoothly. For measurement of aortic calcification, we were considered can be quantified initially. However, measurement of aortic calcification takes a lot of time, and we had a doubt reproducibility. We had to perform a qualitative assessment for aortic calcification.
We examined the association carotid intimal thickening and aortic calcification and pericardial fat, coronary artery calcification, and the base of the brain artery calcification, etc. Pericardial fat was found to be associated with carotid artery intimal thickening. Aortic calcification was observed to be associated with calcification of the base of the brain artery and coronary artery calcification. Aortic calcification was found to be associated with cerebral infarction findings. It is the risk of cardiovascular disease is considered aortic calcification.