2013 Fiscal Year Final Research Report
Prediction of the effect of chemotherapy for hepatocellular carcinoma with new parameters
| Project/Area Number |
23590976
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Gastroenterology
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| Research Institution | Okayama University |
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Principal Investigator |
NOUSO Kazuhiro 岡山大学, 医歯(薬)学総合研究科, 准教授 (10314668)
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| Co-Investigator(Kenkyū-buntansha) |
SHIRAHA Hidenori 岡山大学, 大学病院, 講師 (40379748)
NAKAMURA Shinichiro 岡山大学, 大学病院, 助教 (70514230)
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| Project Period (FY) |
2011 – 2013
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| Keywords | 肝細胞癌 / 化学療法 |
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| Research Abstract |
To improve survival of the patients with advanced hepatocellular carcinoma, we tried to establish markers that could predict the efficacy of chemotherapies. By measuring serum 8 cytokines simultaneously, close correlation was observed between high cytokine expressions and poor prognosis. In addition, comprehensive glycan analysis revealed that survival of the patients with high serum tri-antennary glycan (G2890) expression was shorter than that with the low expression.
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