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2013 Fiscal Year Final Research Report

Novel evaluation method using 3D OCT for safety of drug eluting stent

Research Project

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Project/Area Number 23591045
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Circulatory organs internal medicine
Research InstitutionYamaguchi University

Principal Investigator

OKAMURA Takayuki  山口大学, 医学部附属病院, 助教 (70380011)

Co-Investigator(Kenkyū-buntansha) MATSUZAKI Masunori  山口大学, その他部局等, 名誉教授 (60116754)
Project Period (FY) 2011 – 2013
Keywords虚血性心疾患 / 冠動脈ステント / 光干渉断層法 / 動脈硬化 / 画像診断
Research Abstract

We have developed a novel method to evaluate the tissue coverage using 3-dimensional optical coherence tomography. It had a good correlation to the standard quantitative analysis. The tissue coverage after biolimus- and evarolimus-eluting stent were evaluated by this method and good tissue coverage was revealed at 1-year follow-up. Furthermore, it has been reported that a lipid rich plaque with thin-fibrous cap related to occurrence of acute coronary syndrome and stent-related events. We have developed novel software which demonstrates such vulnerable plaque on 3-dimensional vessel model to facilitate understanding its location.

  • Research Products

    (9 results)

All 2014 2013 2012

All Journal Article (3 results) (of which Peer Reviewed: 3 results) Presentation (6 results) (of which Invited: 1 results)

  • [Journal Article] Serial three-dimensional optical coherence tomography assessment of strut coverage and intraluminal structures after drug-eluting stent implantation2014

    • Author(s)
      Maeda T, Okamura T, Yamada J, Nao T, Tateishi H, Yoshimura M, Oda T, Shiraishi K, Nakashima T, Nakamura T, Miura T, Yano M.
    • Journal Title

      Cardiovasc Interv Ther

      Volume: 29 Pages: 31-9

    • DOI

      10.1007/s12928-013-0209-5

    • Peer Reviewed
  • [Journal Article] Sequel of jailed side branch2014

    • Author(s)
      Tateishi H, Okamura T, Yamada J, Nao T, Maeda T, Oda T, Nakamura T, Miura T, Matsuzaki M, Yano M.
    • Journal Title

      Circ J

      Volume: 78 Pages: 772-4

    • DOI

      10.1253/circj.CJ-13-0709

    • Peer Reviewed
  • [Journal Article] Sirolimus eluting stent fracture detection by three-dimensional optical coherence tomography2012

    • Author(s)
      Okamura T, Matsuzaki M.
    • Journal Title

      Catheter Cardiovasc Interv

      Volume: 79 Pages: 628-32

    • DOI

      10.1002/ccd.23268

    • Peer Reviewed
  • [Presentation] Three-dimensional assessment of Everolimus vs Biolimus eluting stent based on serial optical coherence tomography2014

    • Author(s)
      Maeda T, Okamura T, Yamada J, Nao T, Oda T, Mochizuki M, Tateishi H, Shiraishi K, Nakashima T, Nakamura T, Nishimura S, Yano M.
    • Organizer
      第78回日本循環器学会学術集会
    • Place of Presentation
      東京、東京国際フォーラム
    • Year and Date
      20140321-23
  • [Presentation] The usefulness of three-dimensional optical tomography quantification of fibrous cap; serial change of thin-cap fibroatheroma by statin therapy2014

    • Author(s)
      Nakamura T, Okamura T, Yamada J, Nao T, Oda T, Mochizuki M, Tateishi H, Shiraishi K, Maeda T, Nakashima T, Nishimura S, Yano M.
    • Organizer
      第78回日本循環器学会学術集会
    • Place of Presentation
      東京、東京国際フォーラム
    • Year and Date
      20140321-23
  • [Presentation] Basics of 3-dimensional OCT assessment2013

    • Author(s)
      Okamura T.
    • Organizer
      CCT2013
    • Place of Presentation
      神戸、神戸国際会議場
    • Year and Date
      20131016-18
    • Invited
  • [Presentation] Impact of characterization of tissue prolapse on neointimal formation after drug eluting stent implantation; a serial optical coherence tomography study2013

    • Author(s)
      Nakamura T, Okamura T, Yamada J, Tateishi H,Maeda T, Oda T, Nao T, Shiraishi K, Yoshimura M, Nakashima T, Yano M.
    • Organizer
      EuroPCR2013
    • Place of Presentation
      Paris, France
    • Year and Date
      20130521-24
  • [Presentation] Three-dimensional optical coherence tomography assessment for strut coverage of sirolimus vs everolimus eluting stent at follow-up2013

    • Author(s)
      Maeda T, Okamura T, Yoshimura M, Oda T, Shiraishi K, Nakashima T, Nakamura T, Miura T, Yano M.
    • Organizer
      EuroPCR2013
    • Place of Presentation
      Paris, France
    • Year and Date
      20130521-24
  • [Presentation] Novel Automatic Stent Strut Detection Technique for Rapid Three-dimensional Optical Coherence Tomography to Complex Stenting Procedure2012

    • Author(s)
      Okamura T, Maeda T, Yamada J, Nao T, Suetomi T, Yoshimura M, Hino A, Oda T, Nakashima T, Shiraishi K, Nakashima T, Nakamura T, Nishimura S, Miura T, Matsuzaki M.
    • Organizer
      第76回日本循環器学会
    • Place of Presentation
      福岡、福岡国際会議場
    • Year and Date
      2012-03-17

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Published: 2015-07-16  

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