2013 Fiscal Year Final Research Report
Determination of cellular permeation of medium chain fatty acids
| Project/Area Number |
23591326
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Metabolomics
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| Research Institution | Tokyo University of Pharmacy and Life Science |
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Principal Investigator |
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| Project Period (FY) |
2011 – 2013
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| Keywords | 中鎖脂肪酸 / CaCo-2細胞 |
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| Research Abstract |
Medium chain fatty acids are known as an active component in functional food referred to as Food for Specified Health Uses approved by Consumer Affairs Agency, Government of Japan. As a first step to elucidate the mechanism for the cellular permeation of medium chain fatty acids, a method for the determination of medium chain fatty acids was developed, the measurement uncertainty was predicted, and a cell culture system for the permeation experiment was evaluated. Although a transporter(s) of medium chain fatty acids has not yet been identified, several findings connecting to the mechanism was obtained.
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Research Products
(35 results)
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[Journal Article] Determination of cryptotanshinone, tanshinone I, and tanshinone IIA in Salvia miltiorrhiza by micro HPLC with amperometric detection2013
Author(s)
Chen, X., Kotani, A., Hakamata, H., Du, S., Wang, J., Kusu, F.
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Journal Title
Anal. Lett
Volume: 46
Pages: 605-614
DOI
Peer Reviewed
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[Journal Article] Three-channel column-switching high-performance liquid chromatography with electrochemical detection for determining bioactive redox components in Salvia miltiorrhiza2012
Author(s)
Chen, X., Kotani, A., Hakamata, H., Wang, J., Du, S., Kusu, F.
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Journal Title
J. Chromatogr. A
Volume: 1256
Pages: 105-113
DOI
Peer Reviewed
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