2013 Fiscal Year Final Research Report
Comorbidity and daytime function of patients with narcolepsy
| Project/Area Number |
23591739
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Psychiatric science
|
|---|
| Research Institution | Neuropsychiatric Research Institute |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
OZAKI Akiko 東邦大学, 看護学部, 教授 (30305429)
|
|---|
| Project Period (FY) |
2011 – 2013
|
| Keywords | ナルコレプシー / カタプレキシー / 情動脱力発作 / 診断 / 発症 / QOL / 周期性四肢運動障害 |
|---|
| Research Abstract |
Narcolepsy with Cataplexy (NA-CA) was shown to be complicated with REM sleep behavior disorder and/or Periodic leg movement during sleep (PLMS) possibly due to depressomotor function during sleep, which is influenced by dysfunction of orexin neurons (Hcrt-1). NA-CA with PLMS was characterized by a disrupted nocturnal sleep, however, PLMS did not seem to affect daytime sleepiness and quality of life (QOL) of patients affected with NA-CA.
In order to promote early diagnosis and treatment of NA, improvement of the access to information about both the concept of the disorder and medical institutions specialized in sleep disorders via the Internet would be desirable.
|
